摘要
目的:探讨米氮平对子宫全切术后患者焦虑抑郁及性生活质量的影响。方法:选择2011年1月至2014年8月笔者医院收治的子宫肌瘤行子宫全切术后患者80例,按照随机数字法分为两组,各40例。对照组进行心理学方法干预,观察组则在对照组基础上联合使用米氮平,两组均连续干预治疗12个月,比较两组干预后性状况BISF-W表评分增加比例、恢复性生活时间、性唤起时间、每月性生活频率,干预前后HAMD及HAMA评分变化情况及干预过程中发生的不良反应。结果:干预后两组HAMD及HAMA评分均显著低于干预前(P<0.05),观察组HAMD及HAMA评分低于干预后对照组(P<0.05),观察组性生活恢复时间早于对照组(P<0.05),性唤起时间快于对照组(P<0.05),每月性生活频率多于对照组(P<0.05),观察组性自信、性欲、性高潮、性交流及性交频率加比例均高于对照组(P<0.05),性困惑比例低于对照组(P<0.05),观察组存在睡眠障碍、食欲降低、烦躁、震颤和口干的比例均显著低于对照组(P<0.05)。结论:米氮平能显著改善子宫切除术后患者焦虑抑郁状态,改善患者性功能,提高性生活质量,且治疗后不良反应少,临床安全性高。
Objectives： To investigate the effect of mirtazapine on depression, anxiety and sexual life quality of hysterectomy patients. Methods： 80 cases of uterine fibroids hysterectomy from January 20l 1 to August 2014 were chosen and divided into two groups randomly, with 40 cases in each group. The control group used psychological intervention methods and the observation group used mirtazapine on the basis of psychological intervention meth- ods, all were treated for 12 months. BISF -W Table score increased proportion, time to restore sexual life, arousal time, and monthly sex frequency of the two groups before and after the intervention were compared as well as the HAMD and HAMA score and adverse changes. Results： After intervention, the HAMD and HAMA scores in the two group were significantly lower than these before intervention （ P 〈 0. 05 ）. HAMD and HAMA scores in observa- tion group were lower than these in control group after the intervention （ P 〈 0. 05 ）. Time to restore sexual life in observation group was shorter than that in control group （ P 〈 0. 05 ） ; sexual arousal time in observation group was faster than that in control group （ P 〈 0. 05 ）. Monthly frequency of sexual activity in observation group was more than that in control group （ P 〈 0. 05 ）. The self - confidence, libido, orgasm, sexual intercourse frequency commu- nication and increase rate in the observation group were higher than these in control group （ P 〈 0.05 ）. The proportion of confusion was less than that in control group （ P 〈 0.05 ）. The sleep disorders, loss of appetite, irritability, dry mouth and tremor proportion in observation group were lower than these in control group （ P 〈 0. 05 ）. Conclusion： Mirtazapine can significantly improve anxiety and depression of hysterectomy patients and improve sexual function and sexual life quality, with fewer adverse reactions and higher safety.
出处
《中国性科学》
2016年第9期144-146,共3页
Chinese Journal of Human Sexuality
关键词
米氮平
子宫全切术后
性生活
焦虑
抑郁
Mirtazapine
Hysterectomy surgery
Sexual life quality
Anxiety
Depression
