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替格瑞洛治疗急性ST段抬高型心肌梗死的临床疗效 被引量:1

Clinical Efficacy of Ticagrelor in Treatment of Acute ST Segment Elevation Myocardial Infarction
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摘要 目的 探讨替格瑞洛治疗急性ST段抬高型心肌梗死的临床疗效。方法 选择2014年1月-2015年10月在我院治疗的急性ST段抬高型心肌梗死患者60例的临床资料进行回顾性分析。其中2014年1-11月治疗的30例为对照组,采用氯吡格雷治疗2014年12月-2015年10月治疗的30例为研究组,采用替格瑞洛治疗。随访两组治疗后心血管不良事件发生率、左心室射血分数、ST段回落良好率等。结果 两组治疗后随访心血管不良事件发生率差异无统计学意义(P〉0.05);治疗后1周及1个月,研究组患者ST段回落良好率均显著优于对照组,差异有统计学意义(P〈0.05);治疗后1、3、6个月随访,研究组患者左心室射血分数均显著优于对照组,差异有统计学意义(P〈0.05)。结论急性ST段抬高型心肌梗死患者PCI术后使用替格瑞洛治疗具有加好的临床疗效。 Objective To discuss clinical efficacy of Ticagrelor in the treatment of acute ST segment elevation myocardiahnfarction. Methods The clinical data of 60 patients with acute ST segment elevation myocardial infarction treated in our hospital from January 2014 to October 2015 were retrospectively analyzed. 30 cases treated with clopidogrel from January to November 2014 was the control group; 30 cases treated with Ticagrelor from December 2014 to October 2015 was the study group. The incidence of adverse cardiovascular events, left ventricular ejection fraction, and ST segment drop rate and so on of two groups were followed up. Results The incidence of adverse cardiovascular events after treatment of two groups showed no significant difference ( P 〈 0.05 ) . 1 weeks and I months after treatment, ST segment good drop rates of study group were better than control group (P 〈 0.05 ) . Followed up for 1, 3 and 6 months after treatment, LVEF levers of the study group were better than control group ( P 〈 0.05) . Conclusioll Ticagrelor in treatment of acute ST segment elevation myocardial inthrction is of good clinical efficacy.
作者 潘智卫
出处 《中国卫生标准管理》 2016年第16期110-111,共2页 China Health Standard Management
关键词 替格瑞洛 氯吡格雷 急性ST段抬高型心肌梗死 临床疗效 Ticagrelor, Clopidogrel, Acute ST segment elevation myocardial inthrction, Clinical efficacy
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