摘要
目的对急性脑梗死采用氯吡格雷联合前列地尔治疗的临床效果进行分析。方法选取医院收治的134例急性脑梗死患者,常规阿司匹林治疗的67例纳入对照组,利用氯吡格雷联合前列地尔治疗的67例划入观察组,利用卒中量表NIHSS对治疗后患者神经功能进行评定,并比较其他生化指标。结果两组患者卒中量表评分结果,观察组平均(1.96±0.78)分低于对照组(4.79±1.65)分;比较两组患者治疗后生化指标,CRP、TNF-α、IL-6,观察组低于对照组,差异有统计学意义(P<0.05)。结论氯吡格雷可与前列地尔共同用于急性脑梗死治疗中,对患者神经功能恢复以及其他生化指标的改善都可起到重要作用,可在临床实践中进行推广。
Objective To analyze the clinical effect of acute cerebral infarction treated with clopidogrel combined with alprostadil. Methods 134 cases of acute cerebral infarction patients, conventional aspirin treatment of 67 causes were included in the control group, the therapeutic used of clopidogrel combined with alprostadil in 67 patients assigned to the observation group, neurological function of two groups were evaluated by stroke scale NIHSS, other biochenfical indexes were analyzed and compared. Results Two groups of patients with Stroke Scale score resttlts： The observed group （ 1.96 ±0.78 ） was lower than control group （ 4.79±1.65 ）, compared two groups of patients after biochemical indexes of CRP, TNF-α, IL-6, the observation group was lower than that in the control group, showed significant difference （ P 〈 0.115 ） . Conclusion Clopidogrel and alprostadil jointly for the treatment of acute cerebral infarction, in the recovery of neurological function and other biochentical parameters hnprove can play an important role, it is popularized in clinical practice.
出处
《中国卫生标准管理》
2016年第16期114-115,共2页
China Health Standard Management
关键词
氯吡格雷
前列地尔
急性脑梗死
临床疗效
Clopidogrel, Alprostadil, Acute cerebral infarction, Clinical curative effect
