摘要
研究了一种近红外光谱抗扰动脑血氧分析仪,用于解决常规脑血氧测试方法检测过程复杂、抗干扰措施繁琐等问题。分析与探讨了影响脑血氧检测精度的因素,选择了合适的三波长近红外探测光源(735nm/805nm/850nm)用于该系统。利用氧合血红蛋白和还原血红蛋白在近红外光波段的吸收特性,得到这两种物质的浓度变化量,推算出了影响血氧检测精度的源端干扰表达式。同时,在检测端同步检测环境光,消除了漏光干扰。最后对上位机得到的原始数据与干扰数据进行处理,实现对大脑前额叶脑血氧波动的实时监测。设计了屏气实验以及源端干扰实验,检验了仪器实验结果的正确性。结果表明:本文所设计的脑血氧分析仪可以有效地检测血红蛋白的变化并能通过源端校正算法抑制源端干扰,干扰抑制比可达70%以上,基本实现了对人体无创、实时、准确监测的目的。
A sort of anti-disturbance cerebral oxygen analyzer based on near-infrared spectroscopy was researched to improve conventional test methods in complex measuring process and tedious anti-jam- ming treatment. Some effect factors on cerebral oxygen measuring accuracy were analyzed and a prop- er three-wavelength near-infrared detection light source （735nm/805nm/850nm）was selected to use in the system. On the basis of the absorptivities of HbO2 and HbR in the near- infrared spectra, the vari- ation of the two substance＇s concentration was received, and a source interference expression resulted from the impact of oxygen detection accuracy was calculated. Meanwhile, the ambient light was detec- ted in the terminal simultaneously to eliminate the interference from leaked light. Finally, the original data from a upper computer and the interference data were processed to realize the real-time monito- ring of the blood-oxygen fluctuation in the prefrontal lobe of the brain. A breathlessness experiment and a source interference experiment were performed and the correctness of instrument was verified.The experimental results show that the cerebral oxygen analyzer designed in this paper detects the changes of hemoglobin and eliminates the interference of the source effectively by the proposed anti- disturbance algorithm, and the correcting interference error is about 70% or more, which implements noninvasive, real time and correct monitoring for human body.
出处
《光学精密工程》
EI
CAS
CSCD
北大核心
2016年第8期1846-1853,共8页
Optics and Precision Engineering
基金
吉林市科技计划资助项目(No.2015313013)
吉林大学研究生创新研究计划资助项目(No.2015001)
吉林大学大学生创新创业训练计划资助项目(No.2015650949)
关键词
脑血氧分析仪
近红外光谱
抗扰动
干扰模型
屏气实验
cerebral oxygen analyzer
Near-infrared Spectra （NIRS）
anti-disturbance
interference model
breathlessness experiment
