摘要
目的 探讨前列甘肃地区前列腺癌的诊疗现状。方法 以该地区3家省级医院2010年5月1日至2015年4月30日前列腺癌患者为研究对象,通过对患者发病年龄、血清前列腺特异性抗原（PSA）变化、发病特点、治疗方式、随访情况的分析,总结出该地区前列腺癌的诊疗情况。结果 5年来3家医院共计收治前列腺癌患者915例,年龄为38~96岁,平均71.2岁;血清PSA浓度〈4 ng/ml 49例,4~10 ng/ml 89例,10~20 ng/ml 44例,20~100 ng/ml 317例,〉100 ng/ml 416例;病理确诊患者879例,占96.1%;接受治疗患者882例,占96.4%,其中,药物内分泌治疗825例,占所有接受治疗患者的93.5%。根据血PSA值及转移灶情况,属于稳定期患者约占71%,有27%的患者属于进展期。在接受前列腺癌根治手术的患者中,80%患者无生化或临床复发,无1例死亡。结论 早期前列腺癌确诊成为治疗前列腺癌的主流,而内分泌治疗是前列腺癌的主要治疗方式。
Objective To study the current therapeutic status of prostate cancer in Gansu province,and provide evidence for the di-agnosis and treatment of prostatecancer in this area.Methods Patients with prostate cancer in 3 provincial hospitals of this region from May 1,2010 to April 30,2015 were selected.The onset age,serum PSA,clinical characteristic,treatment and follow-up of the situation were ana-lyzed.Results In five years,a total of 915 cases of patients with prostate cancer have been treated.The age ranges from 38 to 96 years old, the mean age is 71.2 years old.Serum PSA concentration 〈4 ng/ml was in 49 cases,4~10 ng/ml in 89 cases,10~20 ng/ml in 44 cases, 20~100 ng/ml in 317 cases,〉100 ng/ml in 416 cases.Among them,879 cases （96.1%）had pathological diagnosis;882 cases （96.4%） underwent treatment,of which 825 cases （93.5%）of patients were given endocrine treatment.According to the blood PSA and metastases lev-els,patients at stable stage was accounted for about 71%,advanced stage was accounted for about 27%.Among patients given radical prosta-tectomy surgery,80% of patients had no biochemical or clinical recurrence, no one died.Conclusions Early diagnosis and deterministic treatment of prostate cancer have become the mainstream,endocrine therapy is the main treatment of prostate cancer.
出处
《中国老年学杂志》
CAS
CSCD
北大核心
2016年第18期4573-4575,共3页
Chinese Journal of Gerontology
基金
国家自然科学基金(No.81302240)
兰州大学中央高校基本科研业务费(No.lzujbky-2013-134
lzujbky-2014-165)
甘肃省科技计划(No.145RJZA153)
关键词
前列腺癌
前列腺特异性抗原
内分泌治疗
根治性手术
Prostate cancer
Prostate specific antigen
Prostate biopsy
Endocrine therapy
Radical surgery
