摘要
目的研究彩色多普勒超声在对新辅助化疗治疗乳腺癌后疗效评估中的价值。方法对65例乳腺癌患者总共70个肿块使用超声引导,经过粗针穿刺活检后确诊为浸润性乳腺癌后,经过临床评估符合使用新辅助化疗的标准者进行新辅助化疗治疗,在采用化疗前1周以及化疗后手术前进行彩色多普勒超声检查,对血流分布、血流阻力指数以及肿瘤大小进行分析,根据治疗效果将患者分为有效组(CR组+PR组)和无效组(SD组+PD组),对术后的病理结果进行对比分析。结果 CR组有7例。在PR组中,采用新辅助化疗治疗前后病灶的RI值及血流变化均表现出显著相关性(P<0.01),治疗前后病灶的PSV不存在明显的差异;无效组化疗前后病灶内的RI值以及PSV值均无明显相关性。结论使用彩色多普勒超声对乳腺癌的血流参数以及病灶大小检测,具有客观评价的效果,具有良好的临床意义。
Objective To study the value of color doppler ultrasound in the evaluation of curative effect of neoadjuvant chemotherapy for breast cancer. Methods 65 cases of patients with a total of 70 tumors received ultrasound guidance, confirmed after coarse needle biopsy to be invasive breast cancer ,through the clinical evaluation standard with the new adjuvant chemothera- py for neoadjuvant chemotherapy treatment, 1 week before chemotherapy and after chemotherapy, preoperative color doppler ultra- sound examination was conducted, blood flow distribution, blood flow resistance index and tumor size were analyzed, and according to curative effect, the patients were divided into valid group（ CR ＋ PR） and invalid group（SD ＋ PD group） ,postoperative path- ological results were analyzed. Results CR group has 7 cases. In PR group before and after neoadjuvant chemotherapy, RI values and blood flow changes of lesions showed significant correlation（ P 〈 0.01 ） , before and after treatment, PSV of lesions had no ob- vious difference;In invalid group before and after chemotherapy, RI value and PSV had no significant correlation. Conclusion Color doppler flow imaging in the detection of blood flow parameters and lesion size of breast cancer has objective effect and good clinical significance.
出处
《实用癌症杂志》
2016年第9期1459-1461,1465,共4页
The Practical Journal of Cancer
关键词
超声检查
彩色
多普勒
乳腺癌
Ultrasonic examination
Color
Doppler
Breast cancer
