摘要
目的:深入了解186例系统性红斑狼疮(SLE)的发病规律及其临床特点,以提高诊疗水平。方法:对186例SLE患者的一般情况、皮肤黏膜表现、实验室检查等项目进行回顾性分析。结果:所有患者的一般情况、临床特点和实验室检查指标与国内外文献报道基本一致,狼疮活动患者发生血红蛋白降低、红细胞沉降率(ESR)升高、肾功能降低、抗双链脱氧核苷酸(抗dsDNA)阳性的比例高于狼疮未活动患者。结论:SLE是一个终身的,会危及生命的疾病,提高对该病的认识,有助于及时合理的治疗,从根本上改善患者的预后,提高生存率。
Objective： The pattern of disease incidence and clinical characteristics were analyzed in 186 cases of inpatients with SLE in our department during the last 10 years. Methods： The general condition, mucocutaneous manifestations and the results of laboratory tests were retrospectively analyzed in 186 cases of inpatients with SLE. Results： General condition, clinical features and the results of laboratory tests in all patients were similar to those reported abroad. The proportion of patients with reduced hemoglobin, increased ESR, decreased renal function, and anti ds-DNA positive was higher in active than inactive lupus patients. Conclusion： SLE is a life-long and life-threatening disease. Raising the awareness of this disease is helpful for the diagnosis and treatment in a timely manner, and essentially improving both the prognosis and the survival rate of the patients.
作者
李慎秋
李舒康
向微
石小霞
LI Shen-qiu LI Shu-kang XIANG Wei SHI Xiao-xia(Department of Dermatology and Venereology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Chin)
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2016年第10期694-697,共4页
Journal of Clinical Dermatology
关键词
红斑狼疮
系统性
回顾分析
lupus erythematosus, systemic
retrospective study
