摘要
目的探讨孕妇血清维生素D水平与早产的关系。方法采用ELISA法检测337例孕妇血清25羟维生素D[25（OH）D]水平，分析25（OH）D与早产发生的相关性。结果总孕妇的血清25（OH）D中位数及四分位数为46．50（33．95，64．15）nmol／L。其中，187例（55．49％）孕妇血清25（OH）D〈50nmol／L。与中等浓度25（OH）D水平（50～75nmol／L）孕妇相比，低浓度25（OH）D水平（〈50nmol／L）与早产密切相关（OR=2．259，95％CI=1．288-3．962）。结论孕妇维生素D水平低下可能是早产的危险因素之一。
Objective To investigate the correlation of maternal serum 25-OH-vitamin D [25（OH）D] and premature birth. Methods Serum 25（OH）D of 337 pregnant women was measured by ELISA. The correlation of maternal serum 25 （OH）D and premature birth was analyzed. Results The median and quartile of 25 （OH）D levels for the total population were 46.5 （33.95, 64.15） nmol/L. Of 337 pregnant women, 187 cases （55.49%） were in the status of 25 （OH） D defieiency（〈50. 0 nmol/L）. Compared to the women with 25 （OH）D level of 50-75 nmol/L, the pregnant women with vitamin D deficiency（〈50 nmol/L） was significantly correlated with premature birth（OR=2. 259,95% CI = 1. 288 - 3. 962）. Conclusion Vitamin D deficiency may be one of the factors for premature birth.
出处
《江苏医药》
CAS
2016年第18期1989-1992,共4页
Jiangsu Medical Journal
基金
南京医科大学医学科技发展基金重点项目(2015NJMUZD062)
