摘要
目的 探讨畸变产物耳声发射（DPOAE）在听力正常的耳鸣患者中的应用价值。方法 选择98例（156耳）主观性耳鸣患者作为耳鸣组,50例（100耳）无耳鸣症状的听力正常人群作为对照组,比较2组纯音听阈以及DPOAE测试结果;耳鸣组予药物治疗3个疗程后,比较治疗前后各个频率点DPOAE幅值的变化。结果 2组受试者在各频率点纯音听阈值上差异无统计学意义（P〉0.05）;耳鸣组各频率点DPOAE检出率均显著低于对照组（均P〈0.05）;0.25~2.00kHz时2组DPOAE幅值比较差异无统计学意义（P〉0.05）,而3.00~8.00kHz时耳鸣组患者DPOAE幅值显著低于对照组（P〈0.05）。耳鸣组治疗后0.25~2.00kHz DPOAE幅值与治疗前比较差异无统计学意义（P〉0.05）,而3.00~8.00kHz DPOAE幅值较治疗前显著升高（P〈0.05）。结论 DPOAE应用于听力正常的耳鸣患者中有着重要的临床意义,其能够在纯音听阈改变前发现患者早期耳蜗外毛细胞是否存在损伤,并对治疗方案进行评估,可作为耳蜗早期病变的一种客观的检测方法。
Objective To explore the value of distortion product acoustic emission（DPOAE）in tinnitus patients with normal hearing.Methods pure tone audiometry and DPOAE test were performed in 98 patients with subjective tinnitus（tinnitus group,156ears）and 50 normal subjects（control group,100ears）.DPOAE amplitudes were observed before and after 3courses of drug therapy.Results There were no significant differences in pure tone thresholds and 0.25-2.00 kHz DPOAE amplitude between the two groups（P〉0.05）.Compared with control group,DPOAE detection rate and 3.00-8.00 kHz DPOAE amplitude were decreased in tinnitus group（P〈0.05）.After treatment,the 0.25-2.00 kHz DPOAE amplitude was not changed（P〈0.05）,but the 3.00-8.00 kHz DPOAE amplitude was increased in tinnitus group（P〈0.05）.Conclusion The DPOAE has important clinical significance in tinnitus patients with normal hearing.It can be used as an objective detection method to observe the early cochlear outer hair cells and to evaluate the therapeutic regimens before changes in pure tone hearing thresholds.
出处
《实用临床医学（江西）》
CAS
2016年第9期37-39,63,共4页
Practical Clinical Medicine
关键词
畸变产物耳声发射
耳鸣
纯音听阈
听力正常
distortion product otoacoustic emission
tinnitus
pure tone hearing threshold
normal heaving
