摘要
目的探讨直接法与Friedwald公式法测定低密度脂蛋白胆固醇(LDL-C)的差异。方法对该院2015年6—12月门诊方便收集的720份血标本进行血脂检测,包括总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)。根据TG的水平不同,对比分析直接法与Friedwald公式法测定的LDL-C结果,并对血脂水平风险进行评估。结果TG<4.52 mmol/L时,直接法与Friedwald公式法对LDL-C的测定结果差异无统计学意义(P>0.05);TG>4.52 mmol/L时,两种方法对LDL-C的测定结果差异有统计学意义(P<0.05)。结论 Friedwald公式法测定低密度脂蛋白胆固醇适用于TG<4.52 mmol/L的人群,但对于高血脂患者应采用直接法测定LDL-C含量,才能为临床提供可靠的检验数据。
Objective To study the direct method and Friedwald formula method of low density lipoprotein cholesterol(LDL-C). Methods Convenient selection this hospital from June to December 2015 outpatient and 720 cases of blood specimens were collected for detection of blood fat, including total cholesterol(TC), triglyceride(TG), high-density lipoprotein cholesterol(HDL- C). According to different levels of TG, compared the direct method with the results of LDL- C Friedwald formula method, and to evaluate risk of lipid levels. Results TG < 4.52 mmol/L, direct method and Friedwald formula method of LDL- C determination results no significant difference(P > 0.05), compared with no statistical significance. TG> 4.52 mmol/L, two methods for the determination of LDL- C results have significant differences(P < 0.05), compared with statistical significance. Conclusion Friedwald formula method is suitable for determination of low density lipoprotein cholesterol TG < 4.52 mmol/L, but for the determination of the direct method should be used in patients with hyperlipidemia, LDL- C content can provide reliable test data for clinic.
出处
《中外医疗》
2016年第29期45-46,59,共3页
China & Foreign Medical Treatment
