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原发乳腺淋巴瘤的18F-FDG PET/CT表现 被引量:9

^(18)F-FDG PET / CT features of primary breast lymphoma
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摘要 目的探讨原发乳腺淋巴瘤(PBL)的18F-FDG PET/CT显像特征,提高对该病的认识。方法回顾性分析经病理证实的15例PBL的18F-FDG PET/CT显像资料。结果 15例PBL,4例双侧乳腺受侵,11例单侧发病。PET/CT表现主要有三种类型:(1)单发结节或肿块型最常见,占66.7%(10/15),病灶境界清晰,边缘光滑,均为软组织密度;乳头均未见凹陷,邻近皮肤增厚,乳后间隙未见侵犯,乳腺病灶SUV_(max)为16.39(5.92,31.60)。(2)多发结节、肿块型3例,多为数个病灶融合所致;病灶形态、轮廓及密度与单发结节、肿块型相似,而占位效应较后者明显。病灶SUVmax分别为6.95、7.01、33.29。(3)弥漫型2例,范围广,占位效应最明显,乳腺病灶SUVmax分别为8.18、11.52。三种类型间乳腺病灶的SUVmax差异无统计学意义(χ~2=0.737,P=0.692)。临床分期ⅠE期4例,ⅡE期11例;ⅠE期及ⅡE期乳腺病灶的SUV_(max)分别为21.27(7.01,31.60)、11.52(5.92,33.29),差异无统计学意义(Z=-1.044,P=0.296)。结论 PBL的18F-FDG PET/CT表现具有一定特征性:境界清晰、边缘光滑的软组织结节或肿块,18F-FDG摄取较高,有助于PBL的诊断。 Objective To analyze the 18F-FDG PET/CT features of primary breast lymphoma for imaging diagnosis. Methods 18F-FDG PET/CT of 15 patients with histopathologically confirmed primary breast lymphoma was analyzed retrospectively. Results The lesions were bilateral (4) or unilateral (11). PET/CT showed solitary nodule or mass (10/15, 66.7%) or multiple confluent nodules (3/15, 20.0%) with well-defined smooth border, no nipple inversion, skin thickening or invasion of retromammary space. The SUVmax was 16.39(5.92-31.60) in solitary lesions, 6.95, 7.01 and 33.29 in the confluent lesions, respectively. Two patients had diffuse breast infiltration with SUVmax of 8.18 and 11.52, respectively. There was no significant difference among the SUVE (χ2=0.737, P=0.692) of the solitary, multiple and diffuse primary breast lymphoma. The SUVmax of 4 clinical stage IE patients (21.27; 7.01-31.60) was not significantly different (Z=-1.044, P=0.296) from that of 11 stage IIE patients (11.52; 5.92- 33.29. Conclusion The appearance of well-defined breast nodule or mass with high ISF-FDG uptake is helpful for diagnosing primary breast lymphoma.
作者 汤泊 丁重阳
出处 《影像诊断与介入放射学》 2016年第4期293-296,共4页 Diagnostic Imaging & Interventional Radiology
关键词 乳腺 淋巴瘤 正电子发射型体层摄影术 18F氟脱氧葡萄糖 Breast Lymphoma Positron-emission tomography 18F-Fluorodeoxyglucose
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