摘要
目的应用Mod-Tei法和F-Tei法测量中晚孕期胎儿左心室Tei指数,并对这两种方法做可重复性分析,比较两种测量方法的优缺点,分析胎儿左心室Tei指数与孕周的相关性,得到正常中晚孕期胎儿左心室Tei指数正常参考值范围。方法选择接受产前超声检查的正常胎儿180例,孕周18~38周,平均孕周29.84周;孕妇年龄20~34岁,平均年龄26.89岁。选取胎儿五腔心切面,分别采用Mod-Tei法即将多普勒取样器置于主动脉瓣和二尖瓣之间升主动脉壁上采集频谱和F-Tei法即将多普勒超声取样器置于左心室流出道与流入道之间采集频谱。在得到的频谱上分别测量左心室等容收缩时间（ICT）、射血时间（ET）、等容舒张时间（IRT）。等容时间（a）指在心室充盈期的A波结束到下一个E波起始的时间;ET（b）则在左心室流出道切面测得;最终测得Tei指数=（a-b）/b。对两种方法测得结果进行分析比较,分析Tei指数数值与孕周的相关关系。结果胎儿左心室Tei指数的测量可重复性较好,且数值大小与孕周无相关性。ModTei方法较F-Tei方法测量值的变异性更小。应用Mod-Tei法测量180例正常中晚孕期胎儿左心室Tei指数正常值为0.47±0.10。结论应用改良后的方法 （Mod-Tei）测量正常中晚孕期胎儿左心室Tei指数可重复性更好。获得胎儿左心室Tei指数正常参考值可为临床正确评价胎儿左心功能提供帮助。
Objective To obtain the reference valve of normal fetal left ventricular Tei index in advanced gestation by 2methods（Mod-Tei and F-Tei） for analyzing repeatability, and compare the advantages and disadvantages of 2 methods, then analyze the correlation of fetal ventricular Tei index and gestational age. Methods A total of 180 normal advanced fetuses were enrolled. The gestational aged was 18- 38 weeks with mean gestational age of 29.84 weeks. The pregnant women aged20- 34 years old with mean age of 26.89 years old. On the five-chamber view, Mod-Tei method was performed by placing the Doppler sample on ascending aortic wall between aortic and mitral valves, and F-Tei method was performed by placing the Doppler ultrasound between left ventricular outflow and inflow tract to obtain acquisition. Then isovolumetric contraction time（ICT）, ejection time（ET） and isovolumetric relaxation time（IRT） were measured. The isovolumetric（a） referred period from end of A wave to E wave start; ET（b） was measured in section at left ventricular outflow tract; Final ensure Tei index =（a- b）/b. The results of 2 methods were analyzed and compared, and the correlation between the gestational age and Tei index valve was an-alyzed. Results The repeatability of measured fetal ventricular Tei index was fine, there was no correlation between numerical size and gestational age. The variability of Mod-Tei measured was smaller than that of F-Tei. The 180 normal advanced fetal left ventricle Tei index was 0.47 ± 0.10 by Mod-Tei method. Conclusion It is demonstrated that measurement repeatability of normal fetal left ventricular Tei index by Mod-Tei is better than that of F-Tei, which could obtain normal reference values of fetal left ventricular Tei index to help clinical assessment.
出处
《生物医学工程与临床》
CAS
2016年第5期482-486,共5页
Biomedical Engineering and Clinical Medicine
基金
辽宁省科技厅科学技术计划项目(2012225019)
关键词
正常胎儿
左心室功能
TEI指数
心肌做功指数
多普勒超声
normal fetuses
fetal ventricular function
Tei index
myocardial performance index（MPI）
Doppler ultrasound
