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米非司酮联合中药保留灌肠治疗子宫内膜异位症的临床疗效 被引量:8

The clinical curative effect of mifepristone in combination with Herb retention-enema to the treatment of endometriosis
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摘要 目的探讨米非司酮联合中药保留灌肠治疗子宫内膜异位症的临床疗效。方法选择我院2012年1月至2015年12月收治的子宫内膜异位症患者160例为研究对象,将所有患者随机分为对照组和试验组,每组各80例。对照组患者口服米非司酮进行治疗;试验组患者在服用米非司酮的基础上给予中药保留灌肠治疗。两组患者治疗期间采用VAS疼痛视觉模评分评估月经期和非月经期疼痛程度,并在治疗前和治疗结束后4周采用B超测量子宫内膜异位包块的体积及治疗前后激素的变化。结果对照组和试验组患者在治疗后,疼痛评分均较治疗前有所降低,疼痛程度有所缓解,子宫内膜异位病灶体积均有不同程度减小,E_2激素均有降低,但试验组改善程度更明显。结论米非司酮联合中药保留灌肠疗法可明显降低患者的疼痛程度,有效缩小子宫内膜异位病灶,并有效降低E_2激素,具有良好的治疗效果。 Objective To investigate the clinical effect of mifepristone combined with traditional Chinese medicine retention enema in the treatment of endometriosis. Methods Eighty cases of endometriosis in our hospital from January 2012 to December 2015 were selected as the research object, all patients were randomly divided into control group and experimental group, each group of 80 cases. Patients in the control group were treated with mifepristone for treatment; the patients in the experimental group were given traditional Chinese medicine retention enema on the basis of mifepristone. All groups of patients during treatment with VAS pain visual analog score to assess the degree of pain during menstruation and menstrual period, and at the end of treatment and 4 weeks after treatment with hormone changes before and after ultrasound measurements of endometriosis mass volume and treatment. Results The control group and the experimental group of patients before and after treatment, the pain scores were decreased, the degree of pain eased, ectopic endometrium volume decrease, E2 hormone levels were decreased, but the test group improved more significantly. Conclusion Mifepristone combined with traditional Chinese medicine retention enema therapy can significantly reduce the pain of patients, effectively reduce the endometriosis lesions, and effectively reduce the E2 hormone, has a good therapeutic effect.
出处 《临床医学研究与实践》 2016年第20期89-90,共2页 Clinical Research and Practice
关键词 米非司酮 中药保留灌肠 子宫内膜异位症 mifepristone herb retention-enema endometriosis
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  • 1何盛昱.中药联合妈富隆治疗子宫内膜异位症临床观察.中华中西医杂志,2008,9(8):728-730.
  • 2子宫内膜异位症的诊断与治疗规范[J].中华妇产科杂志,2007,42(9):645-648. 被引量:566
  • 3Paris K, Aris A. Endometriosis-associated infertility: a decadeg trend study of women from the Estrie region of Quebec, Canada [ J]. Gynecol Endocrinol,2010,26( 11 ) :838-842.
  • 4Barnhart K, Dunsmoor-Su R, Coutifaris C. Effect of endometri- osis on in vitro fertilization [ J ]. Fertil Steril, 2002,77 ( 6 ) : 1148-1155.
  • 5Practice Committee of the American Society for Reproductive Medicine. Endometriosis and infertility [ J ]. Fertil Steril,2006,86(5 Suppl 1 ) :$156-160.
  • 6Kennedy S, Bergqvist A, Chapron C, et al. ESHRE guideline for the diagnosis and treatment of endometriosis [ J ]. Hum Re- prod ,2005,20 (10) :2698-2704.
  • 7Benschop L, Farquhar C, van der Poel N, et al. Interventions for women with endometrioma prior to assisted reproductive tech- nology [ J ]. Cochrane Database Syst Rev, 2010, (11): CD008571.
  • 8Coccia ME, Rizzello F, Mariani G, et al. Ovarian surgery for bilateral endometriomas influences age at menopause [ J ]. Hum Reprod, 2011,26( 11 ) :3000-3007.
  • 9Shi J, Leng J, Cui Q, et al. Follicle loss after laparoscopic treatment of ovarian endometriotic cysts [ J ]. Int J Gynaecol Ob- stet, 2011,115(3) :277-281.
  • 10Celik HG, Dogan E, Okyay E, et al. Effect of laparoscopic ex- cision of endometriomas on ovarian reserve: serial changes in the serum antimtillerian hormone levels [ J ]. Fertil Steril, 2012,97 (6) : 1472-1478.

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