摘要
川芎嗪为中药川芎中主要的生物碱类化合物,近年来其药理作用受到广泛关注。本文就近年来来川芎嗪抗血栓形成、抗缺血再灌注损伤,对脑、神经、心脏、血管、肺、肝、肾的作用,抗肿瘤、镇痛等方面的研究进展进行综述,为川芎嗪的深入研究及其植物资源的进一步综合开发利用提供参考。
As a major alkaloid in Ligusticum chuanxiong Hort, tetramethylpyrazine has attracted the wide attention in recent years. Studies showed that tetramethylpyrazine has multiple pharmacological effects, such as antithrombosis, antagonizing ischemic reperfusion injury, the effect on the brain, nerve, heart, blood, vessels, lung, liver, kidney, antitumor and analgesia. We made a summary for domestic and foreign study literatures for various pharmacological effects of tetramethylpyrazine in the recent decade, in the expectation of providing the scientific basis for the in-depth studies, as well as the utilization of tetramethylpyrazine and its medicinal resource.
出处
《中国现代中药》
CAS
2016年第10期1364-1370,共7页
Modern Chinese Medicine
基金
国家科技部国际科技合作专项(2010DFA31890)
中国中医科学院自主选题研究项目(ZZ2013003)
关键词
川芎嗪
生物碱类
药理活性
Tetramethylpyrazine
alkaloids
pharmacological activities
