摘要
目的:探讨利用MR灌注加权成像(PWI)评价后循环远端缺血的血液动力学。方法:回顾32例椎基底动脉重度狭窄患者作为病例组,分析PWI和磁共振血管造影(MRA)检查资料,并与30例健康对照组比较,观察血管狭窄,侧支血管,脑血流量(r CBF)、脑血容量(r CBV)、平均通过时间(r MTT)指标。结果:病例组:至少有1支椎基底动脉狭窄>70%,椎动脉重度狭窄17例;基底动脉重度狭窄20例;小脑上动脉重度狭窄8例;大脑后动脉狭窄17例;后交通动脉开放22例;软脑膜动脉的显示11例;微小动脉团显示12例。病例组ROI/额叶白质比值相对于对照组r CBF、r CBV值均下降,MTT值延长,两组参数比较差异有统计学意义(均P<0.05)。结论:PWI结合MRA能够有效地评价后循环远端缺血区域脑组织血流灌注以及侧支循环血流代偿情况,有效的评估缺血区血液动力学。
Objective To explore the way to evaluate hemodynamics of posterior circulation distal ischemia with PWI. Methods Thirty-two patients with vertebral basilar artery severe stenosis were reviewed and compared with thirty normal persons. Information and data of PWI and MRA were collected and analyzed. Following parameters were observed, index of vascular stenosis, collateral vessels, cerebral blood flow （rCBF）, cerebral blood volume （rCBV）, and mean transit time （rMTT）. Results All the patients had at least one vertebral basilar artery with more than 70% stenosis. There were 17 cases with severe vertebral artery stenosis, 20 cases with severe basal artery stenosis, 8 cases with severe superior cerebellar artery stenosis, 17 cases with posterior cerebral artery stenosis, 22 cases with after the traffic artery open, 11 cases with soft meningeal arteries show and 12 cases with small artery show. The ratio of ROI with frontal white matter was lower than the rCBF and rCBV in the country group. MTr value was extended and P value of the parameters in both groups was less than 0.05, reflecting the statistical difference. Conclusions PWI combined with MRA can effectively evaluate the posterior circulation distal ischemia area and tissue perfusion, as well as the hemodynamic status of ischemia area.
作者
张永刚
刘希胜
王敏
许新堂
张秋妹
苗重昌
ZHANG Yong-gang LIU Xi-sheng WANG Min XU Xin-tang ZHANG Qiu-mei MIAO Chong-chang(Department of Radiology, the Affiliated Lianyungang Hospital of Xuzhou Medical College, Lianyungang 222002, Chin)
出处
《实用医学杂志》
CAS
北大核心
2016年第18期2945-2948,共4页
The Journal of Practical Medicine
基金
江苏省卫生厅科研项目(编号:Z201417)
关键词
灌注加权成像
MRA
缺血
椎基底动脉
MTT
Perfusion-weighted MR Imagining
MRA
Ischemia
Vertebral basilar artery
MTT
