摘要
目的探讨宫血宁胶囊在剖宫产即时放置宫内节育器（intrauterine device,IUD）患者中运用对患者炎症反应程度、产褥出血量及恶露持续时间的影响。方法选取温州市龙湾区第一人民医院妇产科210例剖宫产后即时放置宫内节育器的患者作为研究对象,按照随机数字表法分为对照组和观察组,对照组105例患者剖宫产后即时放置宫内节育器,观察组105例患者在对照组患者基础上给予宫血宁胶囊,对比2组患者炎症因子水平,产后出血量,产褥病理以及恶露持续时间等相关指标。结果治疗后,观察组产妇白细胞介素-6（IL-6）、IL-8、IL-10、肿瘤坏死因子α（TNF-α）水平明显低于对照组（P〈0.05）。产后24h出血量明显少于对照组产妇（P〈0.05）。观察组产妇平均体温、白细胞计数、中性粒细胞比例、产褥病率与对照组相比差异无统计学意义。观察组产妇产褥时间〈28d例数明显多于对照组（33 vs.26,P〈0.05）,2组在产褥时间28~42 d、〉42 d方面对比差异无统计学意义。结论宫血宁胶囊有助于减少剖宫产即时放置IUD患者产后出血,抑制炎症反应。
Objective To explore the effect of Gongxuening capsule on inflammation,postpartum hemorrhage and the amount of lochia duration of instant placement intrauterine device（ IUD） in patients with cesarean section. Methods 210 cases of cesarean section immediately placed IUD patients as the research object,were divided into the observation group and the control group by simple random number table method,control group of 105 patients with cesarean section immediate postplacental IUD,observation group were given Gongxuening gapsule on the basis of the patients in the control group. The inflammatory cytokines（ IL-6,IL-8,IL-10,TNF-α） levels,the amount of postpartum hemorrhage,puerperal pathology and duration of lochia related indicators were compared between two groups of patients. Results After treatment,the IL-6,IL-8,IL-10,TNF-α levels in observation group were significantly lower than that of control group（ p〈0. 05）,postpartum hemorrhage 24 h were significantly less than the control group（ p〈0. 05）. There was no significant difference in average body temperature,white blood cell count,neutrophil ratio and puerperal disease rate between observation group and control group. The maternal postpartum 〈28 days wa 33 cases,which was higher than 26 cases in control were,the difference was statistically significant（ p〈0. 05）. There was no significant difference in maternal postpartum from 28 d to 42 d,or 〉42 d between two groups. Conclusion Gongxuening capsule helps reduce postpartum hemorrhage,the degree of inhibition of inflammatory reaction in patients of cesarean section immediately placed IUD.
出处
《中国生化药物杂志》
CAS
2016年第8期85-87,共3页
Chinese Journal of Biochemical Pharmaceutics
基金
温州市龙湾区软科学研究项目(2013R14)
关键词
宫血宁胶囊
剖宫产
宫内节育器
炎症反应
产后出血
Gongxuening capsule
cesarean section
intrauterine device
inflammatory reaction
postpartum hemorrhage
