摘要
目的 探索一种功能性阴茎再造的新术式.方法 解剖4例尸体标本,在尸体上模拟携带神经支配的股薄肌复合携带阔筋膜的股前外侧皮瓣阴茎再造术;以携带腹直肌前鞘的下腹部皮瓣代替股前外侧皮瓣构建犬阴茎再造模型,7个月后以电刺激评估阴茎动态勃起功能,观察记录再造阴茎长度、直径和硬度的变化情况,采用配对t检验进行统计学分析.结果 尸体手术模拟成功,再造阴茎外形良好;犬模型构建成功,静息状态再造阴茎硬度分级为1.2±0.4,电刺激后明显增加至3.4±0.5（P＜0.05）,而长度缩短,直径无明显改变,可以较成功地模拟阴茎勃起过程.结论 皮瓣复合肌肉功能性阴茎再造术具有可行性,为下一步的临床应用提供了理论与技术支持.
Objective To devAop a new approach for functional penile reconstruction.Methods Total penile reconstruction using innervated gracilis muscles and anterolateral thigh （ALT） flap with fascia lata was performed on four human cadavers.Canine models were constructed using gracilis muscles and lower abdominal flap with anterior rectus sheaih,instead of the ALT flap.Seven months later,the erectile function of the neophalli elicited by electrostimulation was evaluated.The length,diameter and stiffness were measured respectively and the results were analyzed statistically using paired-samples t test.Results The penile reconstruction was success with good appearan ce in the cadaveric study.The hardness of the reconstructed penis in canine models was graded as 1.2 ± 0.4 at rest.With the nerve pedicles stimulated,it increased significantly and was graded as 3.4 ± 0.5 （P ＜ 0.05）,while the length shortened and the diameter did not change significantly.A successful erection-mimic course was observed.Conclusions It indicates that penile reconstruction with skin flaps combined with muscle is feasible,serving as a theoretical and technical support for further clinical application.
出处
《中华整形外科杂志》
CAS
CSCD
北大核心
2016年第5期354-358,共5页
Chinese Journal of Plastic Surgery
基金
整形外科医院院所基金（5201010408）
关键词
阴茎再造术
股薄肌
外科皮瓣
阴茎勃起
Reconstruction of penis
Gracilis
Surgical flaps
Penile erection
