摘要
目的：分析妊娠期糖尿病（GDM）患者体内胰岛素样生长因子-1（IGF-1）、胰岛素样生长因子结合蛋白3（IGFBP3、）、生长激素（GH）含量情况以及各项指标与新生儿生长参数间的关系。方法选取我院在2014年11月～2015年7月收治的妊娠期糖尿病患者42例为观察组，血糖正常妊娠期患者40例为对照组。比较两组患者血液中三项指标以及新生儿生长各项生长参数。结果观察组孕妇血液中IGFBP3以及IGF-1都比对照组高，差异具有统计学意义（P＜0.05）。两组孕妇在GH含量以及新生儿生长参数相比差异均无统计学意义（P＞0.05）。结论 IGF-1、IGFBP3与孕妇血糖含量有着较为密切关系，其含量越高出现妊娠糖尿病的风险越大。同时三项指标与新生儿生长参数无明显联系。
Objective To analyze content of vivo insulin-like growth factor -1 （IGF-1）, insulin-like growth factor binding protein 3 （IGFBP3,） growth hormone （GH） in patients with gestational diabetes mellitus （GDM） and their relationship between of fetal growth parameters.Methods 42 cases of patients with gestational diabete in our hospitals from November 2014 to July 2015 to June period were taken as observation group, 40 patients with normal blood glucose during pregnancy were taken as the control group. Two groups were compared in the three indicators of blood and fetal growth and the growth parameters, including head circumference, chest circumference, length and so on.Results The maternal blood insulin-like growth factor binding protein 3 （IGFBP3） and insulin-like growth factor -1 （IGF-1） observation group were signiifcantly higher than the control group, the difference was statistically signiifcant （P〈0.05）. The different of fetal growth and content parameters and growth hormone （GH）between two groups of pregnant women were not significantly （P〉0.05）.Conclusion The insulin-like growth factor -1 （IGF-1）, insulin-like growth factor binding protein 3 （IGFBP3） and blood glucose levels in pregnant women have a more intimate relationship, the higher the content appears the greater the risk of gestational diabetes, while three indicators and neonatal growth parameters no signiifcant relationship.
出处
《中国继续医学教育》
2016年第29期81-82,共2页
China Continuing Medical Education
基金
广西壮族自治区南宁市科学研究与技术开发计划项目(合同编号:20143158)
