摘要
目的分析山东省居民代谢综合征（MS）与微量白蛋白尿（MAU）的关系,为MAU的防控提供依据。方法于2011年在山东省采用4阶段分层随机抽样方法抽取2 184名18-69岁居民作为研究对象,测量其血糖、血脂、24 h尿微量白蛋白和尿肌酐等指标。采用SAS 9.3软件对数据进行统计分析,计量资料的比较用t检验,计数资料的比较用χ2检验,采用二分类logistic模型分析MS的影响因素。结果最终资料完整并符合要求的1 904名研究对象纳入本研究。MS患病率为24.7%。经多因素logistic模型分析,与非MS者相比,MS患者MAU患病风险OR值（95%CI）为2.71（1.69-4.36）。在MS各组分中,中心性肥胖、血压升高和血糖升高均与MAU患病风险存在正相关。此外,与不具有MS组分者相比,具有1、2、3、4和5个MS组分者MAU患病风险OR值（95%CI）分别为1.19（0.55-2.58）、1.32（0.59-2.93）、2.57（1.20-5.51）、3.92（1.67-9.20）和5.66（1.82-17.63）,趋势检验有统计学意义（P〈0.01）。结论 MS是MAU的一个重要危险因素。
Objective To analyze the association of metabolic syndrome（MS） with microalbuminuria（MAU） in residents of Shandong province and to provide the basis for preventing and controlling MAU. Methods In 2011, 4 stage stratified random sampling method was used to select 2 184 residents（18-69 years old）in Shandong province as the subjects. The blood glucose,blood lipid, 24 h urinary micro-albumin excretion（UAE）andurine creatinine（UCr）were detected for each subject. The χ2 and t test were used to analyze the data with SAS 9.3 software, two classification logistic model was utilized to analyze the influencing factors for MS. Results The 1 904 subjects were included in present study, the morbidity of MS was 24.7%（470 cases）. The multivariate logistic regression analysis showed that OR value of MS cases with MAU was 2.71（95%CI： 1.69-4.36）as compare with cases without MS. In MS cases, the central obesity, elevated blood pressure and elevated fasting glucose were correlated positively with the risk of MAU. Additionally, compared with subjects with zero component of MS, the OR values（95% CI）for subjects with 1, 2, 3, 4, and 5 components of MS were 1.19（95%CI： 0.55-2.58）, 1.32（95%CI： 0.59-2.93）, 2.57（95%CI：1.20-5.51）, 3.92（95% CI：1.67-9.20） and 5.66（95% CI：1.82-17.63）, respectively（P 〈0.01）. Conclusion MS is an important risk factor for MAU.
作者
葛增
郭晓雷
陈晓荣
张吉玉
颜流霞
唐俊利
蔡小宁
徐爱强
马吉祥
GE Zeng GUO Xiao-lei CHEN Xiao-rong ZHANG Ji-yu YAN Liu-xia TANG Jun-li CAI Xiao-ning XU Ai-qiang MA Ji-xiang(Department of Cardiovascular Disease Control and Prevention, National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China)
出处
《中国慢性病预防与控制》
CAS
2016年第10期746-749,共4页
Chinese Journal of Prevention and Control of Chronic Diseases
基金
山东省人民政府卫生部联合减盐防控高血压项目
山东省科技发展计划(2012GSF11828)
关键词
24
h尿微量白蛋白
代谢综合征
微量白蛋白尿
24 h urinary micro-albumin excretion
Metabolic syndrome
Microalbuminuria
