摘要
目的通过观察原发性肾病综合征(PNS)患儿血清免疫球蛋白、T淋巴细胞亚群及血液流变学指标的变化,探讨热敏灸疗法在儿童PNS中的作用及干预机制。方法将80例PNS患儿作为观察对象,随机分为治疗组与对照组,每组40例,2组均给予西医常规治疗;治疗组在对照组治疗基础上加用热敏灸治疗。治疗结束后观察PNS患儿血清免疫球蛋白、T淋巴细胞亚群及血液流变学指标的变化。结果治疗组治疗6个月后Ig G高于对照组,P<0.01;治疗组Ig G治疗前后比较,P<0.01;与治疗前比较,治疗后淋巴细胞亚群CD3、CD4、CD4/CD8均有增高,CD8较治疗前下降,P<0.01;治疗组治疗6个月后淋巴细胞亚群CD3、CD4、CD4/CD8与对照组比较均有增高,P<0.01;治疗前2组血浆黏度、全血低切黏度、全血高切黏度、血小板聚集率及纤维蛋白原间比较,P<0.05,治疗后治疗组各项指标均出现显著下降,且均明显低于对照组,P<0.05。结论西医常规方案加用热敏灸疗法,能够显著改善PNS患儿免疫球蛋白,T淋巴细胞亚群,血液流变学等指标。
Objective In order to discuss the effect of moxibustion on temperature-sensitive points therapy on PNS in children,the experiment observed the changes of serum immunoglobulin,T lymphocyte subsets and blood rheology indexes in children with PNS. Methods The 80 cases of PNS children were randomly divided into treated group and contrast group. Each group had 40 cases. Both two groups were treated in the same way of western medicine routine treatment,while the treated group was added another way of moxibustion on temperature-sensitive points therapy.After the treatment,pay attention to the changes of serum immunoglobulin,T lymphocyte subsets and blood rheology indexes in children with PNS. Results After 6-months-treatment,Ig G of the treated group was higher than the contrast group,which implied that the difference was significant,P〈0. 01. Before and after the treatment,there was also significant with the treated groups Ig G,P〈0. 01. Compared with the condition before treatment,the number of lym-phocyte subsets CD3,CD4,CD4/CD8,CD8 became higher,while the number of CD8 became lower. This difference was significant,P〈0. 01. After 6-months-treatment,each number of lymphocyte subsets CD3,CD4,CD4/CD8 in the treated group were increased comparing with the contrast group,which differences was significant,P〈0. 01. Additionally,the differences between the two groups of patients plasma viscosity,whole blood viscosity,whole blood viscosity,platelet aggregation rate and fibrinogen before the treatment were also significant,P〈0. 05. After the treatment,the indicators of the treated group were not only obviously decreased,but also evidently lower than the contrast group. These differences were significant,P〈0. 05. Conclusion Western medicine routine treatment with moxibustion on temperature-sensitive points therapy can visibly improve the immune globulin,T lymphocyte subsets,blood rheology and other indicators of children with PNS.
出处
《长春中医药大学学报》
2016年第5期973-975,共3页
Journal of Changchun University of Chinese Medicine
基金
国家中医药管理局全国名老中医药专家传承工作室项目([2014]20)
关键词
热敏灸
原发性肾病综合征
免疫功能
血液流变学
moxibustion on temperature-sensitive points
primary nephrotic syndrome
immune function
blood rheology
