摘要
系统性红斑狼疮(systemic lupus erythematosus,SLE)是一种累及多器官多系统的自身免疫性疾病,尽管近年来目标治疗策略指导下的治疗已经使患者的预后得到了很大改善,但目前仍然有很多临床重要问题没有解决。本文对2015年SLE发病机制、神经系统和肾脏受累、合并妊娠、治疗(生物制剂、新的小分子药物和细胞治疗)及预后等进展进行总结。
Systemic Lupus Erythematosus （SLE） is an autoimmune disease characterized by multi-organ damage. Although the prognosis of patients has been significantly improved during the recent decades with the treat-to target strategies, many important questions need to be resolved. In this article, research on the pathogenesis, clinical manifestations, pregnancy and prognosis were reviewed. The recent progress in the treatment, especially the biologics, new oral small molecules and cell-based therapy were summarized.
出处
《中华临床免疫和变态反应杂志》
2016年第3期276-280,共5页
Chinese Journal of Allergy & Clinical Immunology
关键词
红斑狼疮
系统性
研究
进展
lupus erythematosus, systemic
research
progress
