摘要
目的:观察及比较不同黄体酮剂量在先兆流产患者中的应用效果。方法:选取2014年7月-2016年7月本院收治的150例早孕先兆流产患者为研究对象,将其按照随机数字表法分为A组(20 mg/d)、B组(30 mg/d)和C组(40 mg/d),每组50例,比较三组治疗总有效率、并发症发生率、治疗前和治疗后血液相关指标。结果:B组与C组治疗总有效率均明显高于A组,A组与B组并发症发生率均明显低于C组,B组与C组治疗后1、3 d血清抑制素A(INHA)、蛋白A(PAPP-A)及孕酮(P)均高于A组,血清Th1/Th2指标均好于A组,差异均有统计学意义(P<0.05)。结论:30 mg/d黄体酮在先兆流产患者中的应用效果较好,对先兆流产患者疾病相关血液指标的调节作用也更好,因此应用价值相对更高。
Objective：To observe and compare the application effect of different doses of Progesterone in patients with threatened abortion.Method：A total of 150 patients with threatened abortion in our hospital from July 2014 to July 2016 were selected as the research objects,and they were randomly divided into group A（20 mg/d）,group B（30 mg/d）and group C（40 mg/d）,50 cases in each group,then the total effective rates, complication rates,blood related indexes before the treatment and at different time after the treatment of three groups were compared.Result：The total effective rates of group B and goup C were both higher than that of group A, the complication rates of group A and group B were both lower than those of group C,serum INHA,PAPP-A and P of group B and group C at first and third day after the treatment were all higher than those of group A, serum Th1/Th2 indexes were all better than those of group A,the differences were all significant（P〈0.05）. Conclusion：The application effect of different doses of Progesterone in patients with threatened abortion are better, and its regulating effect for the disease related blood indexes of patients with threatened abortion are better,so its application value is higher.
出处
《中国医学创新》
CAS
2016年第29期112-114,共3页
Medical Innovation of China
基金
江西省萍乡市科技局社会发展科技计划项目(20150051)
关键词
不同剂量黄体酮
先兆流产
应用效果
Different doses of Progesterone
Threatened abortion
Application effect
