摘要
以4-甲基-2,6-二甲酰基苯酚和1,3,3-三甲基-2-亚甲基吲哚啉为原料合成了能同时识别Cu^(2+)和水合肼的螺吡喃双功能探针L,其结构经~1H NMR、^(13)C NMR、FT-IR和H RMS进行了表征。通过紫外-可见光谱法、荧光光谱法、核磁共振和质谱研究了探针L在p H=7.40的Tris-HCl-乙醇溶液(1∶1,V/V)中与19种金属离子、18种阴离子及9种胺类化合物的识别特性。结果表明,在p H=7.40的Tris-HCl-乙醇溶液(1∶1,V/V)中,相对于其它干扰离子,L对Cu^(2+)和水合肼具有特异选择性和专一性,制成试纸能够实现肉眼识别检测含μmol/L Cu^(2+)的水样。尤为重要的是,制备的含L的TLC板能实现在紫外灯下对液体和气体水合肼的肉眼识别。将L应用于水样和药物中Cu^(2+)或水合肼测定的回收率在83.5%~111.0%之间,相对标准偏差(RSD)<4%,说明L适用于环境污染监测和药物分析检测,具有潜在的应用前景。
A spirobenzopyran-based probe（ L） for the detection of Cu^2＋ and hydrazine was synthesized by using 4-methyl-2,6-diformylphenol and 1,3,3-trimethyl-2-methyleneindoline, and its structure was characterized by1 H NMR,^13 C NMR,FT-IR and H RMS（ ESI-MS）. The recognition properties of the probe L with nineteen kinds of metral ions,eighteen kinds of anion ions and nine kinds of amine compounds had been investigated in Tris-HCl（ p H = 7. 40）-ethanol solution（ 1 ∶ 1, V / V） by UV-Vis, fluorescence spectrophotometry,1H NMR titration and MS. The results showed that the probe L exhibited higher selectivity and sensitivity towardsCu^2＋ and hydrazine over other interfering objects in Tris-HCl（ p H = 7. 40）-ethanol solution（ 1∶ 1,V / V）,and the color changes of L caused byCu^2＋ and hydrazine could be observed by naked eyes. Thus,L could be loaded as test paper for detectingCu^2＋ at μmol / L level in water solution by naked eyes. Notably,probe L could be used to detect hydrazine in liquid and gas state with different concentrations by detecting the color changes from readily prepared TLC plates. On the basis of this,the probe L was used in the determination ofCu^2＋ in the water and drug samples with recoveries of 83.5%-111.0% and RSD of 4.0%.The results showed that this probe L had potential applications in the monitoring of environmental pollution and the analysis ofCu^2＋ and hydrazine in drug.
作者
余光勤
袁泽利
杨洁
吴庆
胡庆红
张铭钦
江波
卫钢
YU Guang-Qin YUAN Ze-Li YANG Jie WU Qing HU Qing-Hong ZHANG Ming-Qin JIANG Bo WEI Gang(School of Pharmacy, Zunyi Medical University Zunyi 563003, China CSIRO Manufacturing Flagship, PO Box 218, Lindfield, NSW 2070, Australia)
出处
《分析化学》
SCIE
EI
CAS
CSCD
北大核心
2016年第10期1495-1503,共9页
Chinese Journal of Analytical Chemistry
基金
国家自然科学基金(No.81360471)
教育部春晖计划(Nos.Z2014089,Z2014095)资助项目~~
关键词
螺吡喃
探针
CU^2+
水合肼
合成
Spirobenzopyran
Probe
Copper（Ⅱ）
Hydrazine
Synthesis
