期刊文献+

儿童眼部肿瘤504例临床病理学分析 被引量:20

Clinical and pathological analysis of ocular tumors in 504 children cases
原文传递
导出
摘要 目的 分析儿童眼部肿瘤的临床病理学特点.方法 回顾性系列病例研究.收集2002年1月至2014年12月在天津市眼科医院存档,并经手术治疗后病理检查确诊的504例(506只眼)眼部肿瘤患儿的临床资料.分析肿瘤的发生部位、临床特点及病理分型.结果 504例儿童眼部肿瘤患儿中,男性246例(248只眼),女性258例(258只眼).患儿就诊年龄为4个月至14岁,平均年龄为6.4岁.眼睑和眼表肿瘤328例(330只眼),占65.1%,其中恶性肿瘤2例(0.6%),其余均为良性肿瘤,位居前4位的是角膜皮样瘤、皮样囊肿、色素痣和毛母质瘤;眼眶肿瘤123例(123只眼),占24.4%,其中恶性肿瘤13例(10.6%),其余均为良性肿瘤,前4位依次为皮样囊肿、淋巴管瘤、血管淋巴管瘤和静脉性血管瘤;而在眼内肿瘤53例(53只眼,10.5%)中,恶性肿瘤41例(77.4%),均为视网膜母细胞瘤.结论 儿童眼部肿瘤以先天性和胚胎性肿瘤为主,其中以眼睑和眼表肿瘤最多见.良性肿瘤以角膜皮样瘤、皮样囊肿多见,恶性肿瘤主要为视网膜母细胞瘤、横纹肌肉瘤等. Objective To analyze the clinical features and pathological classification of chlidren's ocular tumors.Methods Retrospective case series study.Five hundred and four cases (506 eyes) of ocular tumor with biopsy-proven in children below 14 years old between January 2002 and December 2014 from Tianjin Eye Hospital were performed to retrospectively investigated the lesion location,clinical features and histopathologic classification of these lesions.Results Of 504 cases there were 246 boys (248 eyes) and 258 girls (258 eyes) patients.The mean age at diagnosis was 6.4 years,ranged from 4 months to 14 years.Of 328 cases (65.1%) of eyelid and ocular surface,2 cases (0.6%) were malignant tumors and other tumors were all benign tumors.The leading four tumors were corneal dermoid,dermoid cysts,nevus and pilomatricoma.Of 123 cases (24.4%) of orbital tumors,13 cases (10.6%) were malignant tumors and other tumors were all benign tumors.The leading four tumors were dermoid cysts,lymphangiomas,hemolymphangioma and venous hemangioma.Of 53 cases (10.5%) of intraocular tumors,41 cases (77.4%) were malignant tumors which were all retinoblastoma.Conclusions Most of children's ocular tumors were congenital and embryonic tumors.The most common ocular tumors of 504 children patients were from eyelid and ocular surface.Corneal dermoid and dermoid cysts were the most benign ones.Retinoblastoma and rhabdomyosarcoma were the most malignant ones.
出处 《中华眼科杂志》 CAS CSCD 北大核心 2016年第10期764-768,共5页 Chinese Journal of Ophthalmology
关键词 眼肿瘤 皮样囊肿 视网膜母细胞瘤 横纹肌肉瘤 儿童 Eye neoplasms Dermoid cyst Retinoblastoma Rhabdomyosarcoma Child
  • 相关文献

参考文献15

  • 1Zimmermann-Paiz MA, de la Riva JC G. Conjunctival tumors in children: histopathologic diagnosis in 165 cases[J]. Arq Bras Oftalmd, 2015, 78(6): 337-339. DOI: 10. 5935/ 0004-2749. 20150089.
  • 2Levy R, Lara-Corrales I. Melanocytic Nevi in Children: A Review[J]. Pediatr Ann, 2016, 45(8): e293-298. DOI: 10. 3928/19382359-20160720-07.
  • 3李秀琪,王太玲,李无言,郭鑫,于浩,侯典举,王佳琦.眼睑分裂痣的手术方法选择[J].中华整形外科杂志,2015,31(2):96-99. 被引量:12
  • 4王毅,赵海萍,朱慧,李月月,肖利华.眼眶复发性皮样囊肿的临床特征与治疗[J].中华眼科杂志,2010,46(4):295-298. 被引量:6
  • 5容维宁,孙丰源,唐东润.眼眶淋巴管瘤的临床分析[J].天津医科大学学报,2010,16(3):538-540. 被引量:3
  • 6Chen L, He Y, Sun S, et al. Vasculogenic mimicry is a major feature and novel predictor of poor prognosis in patients with orbital rhabdomyosarcoma[J]. Oncol Lett, 2015, 10(3): 1635-1641. DOI: 10. 3892/ol. 2015. 3469.
  • 7魏秋彩,李晓华,郝远瑞.儿童眼部肿瘤213例的病理学分类[J].中华眼科杂志,2013,49(1):37-40. 被引量:17
  • 8Maka E, Luk6ts O, T6th J, et al. Orbital tumour as initial manifestation of acute myeloid leukemia: granulocyticsarcoma: case report[J]. Pathol Oncol Res, 2008, 14(2): 209-211. DO1: 10. 1007/s12253-008-9028-x.
  • 9Qiao PF, Shen LH, Gao Y, et al. Alveolar soft part sarcoma: Clinicopathological analysis and imaging results[J]. Oncol Lett, 2015, 10(5): 2777-2780. DOI: 10. 3892/ol. 2015. 3694.
  • 10何为民,罗清礼,夏瑞南,杨光华.眼眶复发性腺泡状软组织肉瘤二例[J].中华眼科杂志,2004,40(12):848-850. 被引量:2

二级参考文献51

共引文献36

同被引文献113

引证文献20

二级引证文献34

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部