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襄阳地区妊娠期妇女碘营养状态与甲状腺功能相关指标探讨 被引量:7

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摘要 目的研究襄阳市妊娠妇女在不同妊娠时期的甲状腺功能及尿碘状况,建立襄阳地区妊娠月份特异性血清甲状腺激素的正常参考范围,为实施妊娠妇女甲状腺功能筛查或碘营养监测提供依据。方法选取2013年3月-2015年12月在该院就诊,进行妊娠常规检查的妇女600例为研究对象,其中非妊娠妇女150例,妊娠妇女450例。对参与试验者进行尿碘酸消化砷——铈接触法检测和血清化学发光法检测,分别记录其体内游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、促甲状腺激素(TSH)和尿碘相关数据。结果妊娠早、中、晚期受测妇女的尿碘中位数及非妊娠妇女的尿碘中位数分别为176、169、157及174μg/L;妊娠早、中、晚期妇女TSH水平分别为0.13~3.28,0.24-3.84和0.34-4.05mIU/L,FT3水平分别为3.11-9.53,2.84-8.62和2.79-8.32pmol/L.FT4水平分别为10.20-21.58,10.09-17.83和9.70-16.82pmol/L。结论襄阳市孕妇碘营养状态处于适宜程度。妊娠期妇女甲状腺功能有着明显变化,针对襄阳地区人群碘摄入、生活饮食、经济文化等不同于其他地区,有必要建立襄阳市妊娠月份特异性的血清TSH、FT3、FT4正常参考范围。
出处 《中国妇幼保健》 CAS 2016年第21期4375-4377,共3页 Maternal and Child Health Care of China
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