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气滞胃痛颗粒与奥美拉唑联合治疗胃食管反流病的临床观察 被引量:10

Clinical Observation on Qizhi Weitong Granule combined w ith Omeprazole in the Treatment of Gastroesophageal Reflux Disease
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摘要 目的探讨气滞胃痛颗粒与奥美拉唑联合治疗胃食管反流病的临床疗效。方法选择2013年4月—2015年4月吉安市青原区人民医院收治的120例胃食管反流病患者,随机均分为对照组与研究组各60例。对照组给予奥美拉唑20 mg/次,2次/日;研究组在对照组用药基础上,加用气滞胃痛颗粒5 g/次,3次/日。2组均8周为1个疗程。对比2组临床疗效、胃镜疗效及症状复发情况。结果总有效率93.3%;研究组胃镜总有效率95.0%;经随访6个月,研究组复发4例,对照组复发13例。研究组临床疗效、胃镜疗效的总有效率均优于对照组(P<0.05),复发率低于对照组(P<0.05)。结论气滞胃痛颗粒与奥美拉唑联合使用对胃食管反流病具有较好疗效,值得临床推广。 Objective To investigate the clinical effect of Qizhi Weitong granule combined with omeprazole in the treatment of gas- troesophageal reflux disease. Methods Selecting 120 cases of gastroesophageal reflux disease patients from April 2013 to April 2015 in Qingyuan District People's Hospital, they were randomly divided into the control group and the study group. The control group was treated with omeprazole. The study group was given Qizhi Weitong granule and omeprazole. The clinical effect, the efficacy of en- doscopy and symptom recurrence cases were compared. Results The total effective rate of the clinical curative effect and endoscopic treatment in the study group were better than those in the control group (P 〈 0.05) , the recurrence rate of the study group was low- er than that of the control group (P 〈 0.05) . Conclusion The combined use of Qizhi Weitong granule and omeprazole in treating gastroesophageal reflux disease has good curative effect, and is worthy of promotion.
作者 王九裕 WANG Jiuyu(Department of Internal Medicine, Qingyuan District People's Hospital, Jiangxi Province, Ji'an 343000, Chin)
出处 《中国中医药现代远程教育》 2016年第19期86-87,共2页 Chinese Medicine Modern Distance Education of China
关键词 奥美拉唑 气滞胃痛颗粒 胃食管反流病 反酸 omeprazole Qizhi Weitong granule gastroesophageal reflux disease sour regurgitation
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