摘要
目的主要研究自拟消脂汤联合西药针对男性高脂血症患者的临床疗效及不良反应并加以总结,为相关医务人员提供参考。方法将80例符合病例要求的男性高脂血症患者均分为两组,通过相关诊断治疗及临床表现对两组患者在治疗9周和18周时的治疗前后高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)以及总胆固醇(TC)和三酰甘油(TG)四项指标的变化及患者的不良反应情况进行观察分析,同时对患者酸激酶(CK)、谷丙转氨酶(ALT)、以及血清肌酐(Scr)和谷草转氨酶(AST)四项指标加以检验。结果两组通过长达18周的治疗,研究组其LDL-C、TG、TC各项指标经治疗后分别有所降低,治疗前后各项指标对比差异明显,相关数据资料进行比较纳入统计学分析有意义(P<0.05);组间相比,研究组LDL-C与TC两项指标降低幅度较于对比组有着明显提高,两组数据进行比较纳入统计学有意义(P<0.05)。另外在患者不良反应率记录中对比组明显高于研究组,组间对比有差异纳入统计学意义(P<0.05)),其中产生的不良反应皆可自行缓解。结论经研究表明自拟消脂汤联合西药治疗男性高脂血症比单单使用西药降脂治疗更具临床应用价值,其中安全性也具有一定保障,出现不良反应的情况较少,值得更加广泛的借鉴和运用。
Objective To study the clinical effect of self-made Xiaozhi decoction combined with Western medicinein the treatment of male hyperlipidemia and to summarize adverse reactions, in order to provide reference for the related medical personnel. Methods 80 cases of patients with male hyperlipidemia were divided into two groups. Through related diagnosis and treatment and clinical mani-festations, at the end of 9 weeks and 18 weeks of treatment, four indexes of high density lipoprotein cholesterol（HDL-C）, low density lipoprotein cholesterol（LDL-C） and total cholesterol（TC） and 3 acyl glycerine（TG） and changes of blood adverse reaction condition were observed and analyzed, at the same time, the patients ＇ creatine kinase（CK）, alanine aminotransferase（ALT） and serum creatinine（ SCR） and aspartate aminotransferase（ AST） four indicators were inspected. Results After 18 weeks of treatment, the LDL-C, TG, TC index of the study group respectively decreased. Before and after treatment, each index had obviousdiffer-ence, and the related data was included in the statistical analysis of significance（ P 〈0.05）. The LDL-C and TC index of the study group reduced amplitude comparing with the control group increased markedly, and the data of the two groups of comparison into the difference between two groups was statistically significant（ P 〈0.05）. In addition, the adverse reaction rate of patients in the record of the control group was significantly higher than those of the study group, and the difference between the groups was statistically sig-nificant（P 〈0.05）, which can alleviate the adverse reactions. Conclusion The study showed that the self-made Xiaozhi decoction combined with Western medicine in the treatment of male hyperlipidemia was better than Western medicine in lipid-lowering, has clinical application value, certain security and fewer adverse reactions, and is worthy of more extensive reference and use.
作者
张群峰
ZHANG Qunfeng(Department of Internal Medicine, Guangchang Hospital of Traditional Chinese Medicine, Jiangxi Province, Guangchang 344900, Chin)
出处
《中国中医药现代远程教育》
2016年第20期87-88,共2页
Chinese Medicine Modern Distance Education of China
关键词
消脂汤
男性
高脂血症
降血脂药
痰证
Xiaozhi decoction
male
hyperlipidemia
hypolipidemic drugs
phlegm syndrome
