摘要
科学的进步不但要求对物质的整体特征进行鉴定和测定 ,同时还要求对单分子化学和物理性质进行深入探索。在单分子水平对物质进行研究 ,是一项重要的学科前沿交叉领域 ,对分子工程学、分子生物学、分子医学、纳米材料和信息科学具有非常重要的意义。本文评述近年来溶液中单分子检测研究的最新进展 ,包括激光诱导荧光检测、电化学检测及我们最近提出的化学发光检测等。
Advances in science require not only the identification and detection of material's ensemble character but also the deep exploration of its single-molecule chemical and physical properties. As a frontier cross-discipline research activity, studying substances at the single-molecule level, is very important to research the molecular engineering, molecular biology, molecular medicine, nanostructured materials and information. The new progress for detecting single-molecule in solution, including laser-induced fluorescence detection, electrochemical detection and chemiluminescence detection, has been reviewed in this paper and the prospects on the frontier of the research area have also been discussed.
出处
《分析化学》
SCIE
EI
CAS
CSCD
北大核心
2002年第8期1000-1004,共5页
Chinese Journal of Analytical Chemistry
基金
国家自然科学基金资助项目 (No .2 0 0 750 17)
关键词
单分子检测
激光诱导荧光
电化学
化学发光
分析化学
溶液
single-molecule detection
laser-induced fluorescence
electrochemistry
chemiluminescence
review
