摘要
目的:探讨参术冠心通颗粒对提高稳定性心绞痛运动耐量的临床观察。方法:选取2013年3月-2016年3月我院治疗的冠心病稳定性心绞痛患者90例作为研究对象,随机分为观察组和对照组各45例。两组均进行常规抗血小板、控制血压、缓解心绞痛等治疗,观察组在常规治疗基础上给予参术冠心通颗粒剂,对照组给予安慰剂。运用电脑平板运动仪测评平板运动总时间和最大负荷量,对心绞痛进行疗效评价。结果:观察组治疗12周的平板运动时间为(629.56±122.47)s,对照组为(545.76±139.65)s,观察组治疗12周平板运动时间大于对照组,差异有统计学意义(P<0.01)。观察组治疗12周的最大负荷量(12.75±2.54)明显高于对照组(11.53±2.46),差异有统计学意义(P<0.05)。观察组治疗的总有效率(88.89%)明显高于对照组(60.00%),差异有统计学意义(P<0.05)。结论:参术冠心通颗粒治疗稳定性心绞痛患者,可以明显提高患者的运动耐量,治疗心绞痛的疗效显著。
Objective ： To perform a clinical trial of shenzhu guanxintong granules in improvement of exercise tolerance of patients with stable angina. Methods： A total of 90 patients with stable angina, hospitalized in our hospital from March 2013 to March 2016, were randomly divided into trial and control groups, 45 for each. All the patients received therapies such as antiplatelet, control of blood pressure and relieving of angina, based on which the patients in trial group were treated with shenzhu guanxintong granules, while those in control group with a placebo. The total plate movement time and maximum load were measured by using computer plate movement instrument to evaluate the curative effect on angina. Results： The total plate movement time of trial and control groups after treatment for 12 weeks were（629.56 ± 122.47） s and（545. 76 ± 139.65） s respectively（P〈0.01）. However, the maximum load and total effective rate of trial group [（12.75 ± 2.54）, and 88.89% respectively] were significantly higher than those of control group [（11.53 ±2.46） and 60.00% respectively, P〈0.05]. Conclusion： Shenzhu guanxintong granules improved the exercise tolerance of patients with stable angina significantly, which showed obviously curative effect on angina.
作者
高红
Gao Hong(The Third People＇s Hospital in Benxi City, Liaoning Benxi 117022, China)
出处
《中国执业药师》
CAS
2016年第10期10-12,共3页
China Licensed Pharmacist
关键词
参术冠心通颗粒
稳定性心绞痛
运动耐量
Shenzhu Guanxintong Granules
Stable Angina
Exercise Tolerance
