摘要
目的分析和研究胞浆内单精子注射技术中卵母细胞形态学特性对其结局的影响。方法此次研究对象一共200例,分成试验组和对照组,每组各100例。对照组采用卵母细胞注射。试验组采用卵母细胞胞浆内单精子注射。测量和统计这两组中,胚胎的发育情况以及胚胎成型后出现的结果等。结果由研究结果显示,试验组严重畸精症患者采用经卵母细胞胞浆内单精子注射后,由胚胎的发育情况比较可知,胚胎的卵裂率、优质胚胎率、囊胚形成率、胚胎种植率等情况明显高于对照组,存在差别,P<0.05。对照组严重畸精症患者采用卵母细胞注射后,胚胎成型结果比较可知,对照组出现流产率高达31%、妊娠率仅有39%,差别可见,P<0.05。结论根据研究结果,胞浆内单精子注射技术中卵母细胞形态学特性对其后胚胎质量的影响极大,在一定程度上增加了精子的着床率,降低了流产率。改善了严重畸精症患者的生育状况,减少了患者痛苦,提高了患者的生活质量。
Objective：To analyze and study the effect of oocyte morphology on the quality of single sperm injection. Methods：A total of 200 cases were divided into experimental group and control group,100 cases in each group. Control group was injected with oocytes. In the experimental group,the oocytes were injected with a single sperm injection. Measurement and statistics of the two groups,the development of the embryo,as well as the results of the embryo after the formation of the results,etc. Results：The results of this study shows that,test group of severely abnormal azoospermia patients with after oocyte cytoplasm intracytoplasmic sperm injection,by the embryo is known,embryo cleavage rate,high quality embryo rate and blastocyst formation rate and embryo implantation rate was significantly higher than that in the control group. There is a difference,P〈0.05）. Control group of severely abnormal azoospermia patients by injected oocytes and embryos forming comparison shows that,control group had the abortion rate up to 31%,pregnancy rates of only 39%. The differences are visible,P〈0.05）. Conclusion：According to the results of the study,the morphological characteristics of the oocytes in the cytoplasm of single sperm injection technology have great influence on the quality of the subsequent embryos,and the implantation rate of sperm is increased to a certain extent,and the abortion rate is reduced. To improve the reproductive status of the patients with severe abnormal azoospermia,reduce the pain of patients,improve the quality of life of patients.
出处
《中国优生与遗传杂志》
2016年第10期115-117,共3页
Chinese Journal of Birth Health & Heredity
