摘要
目的：了解个体化营养支持治疗重症急性胰腺炎的疗效，为该疾病提供有效的营养支持疗法。方法97例重症急性胰腺炎患者被随机分为观察组51例和对照组46例；对照组给予标准全胃肠外营养支持；观察组给予相同热量、氮量的阶段性个体化营养支持。在治疗前后检测两组的血红蛋白（Hb）、白蛋白（ALB）、前白蛋白（PA）、转铁蛋白（TFN）水平。观察两组的血淀粉酶恢复时间、恢复经口进食时间、住院时间和住院费用，观察两组治疗期间胃肠道并发症发生情况。结果与治疗前相比，观察组和对照组治疗后的Hb、ALB、PA、TFN 均升高（t ＝4．114、7．540、5．556、8．307和1．994、3．970、2．906、5．099，均 P ＜0．05）；治疗后观察组的 ALB、PA、TFN 均高于对照组（t ＝2．249、2．256、3．630，均 P ＜0．05）；观察组的血淀粉酶恢复时间、恢复经口进食时间、住院时间、住院费用均低于对照组（t ＝3．191、5．245、4．846、8．762，均 P ＜0．05）。观察组的胃肠道并发症发生率11．8％（6／51），对照组的胃肠道并发症发生率15．2％（7／46），两组差异无统计学意义（χ2＝0．248，P ＞0．05）。结论在治疗重症急性胰腺炎中，个体化营养支持具有更好的疗效，并发症发生率较低，具有良好的临床应用价值。
Objective To learn the effect of individualized nutritional support in the treatment of severe acute pancreatitis and provide an effective nutritional support therapy for the disease.Methods 97 patients of severe acute pancreatitis were randomly divided into 51 cases of observation group and 46 cases of control group.The control group was given standard parenteral nutrition.The observation group was given the same heat and support stage of individual nutrition nitrogen.Hemoglobin （Hb）,albumin （ALB）,pre albumin （PA）and transferrin （TFN）of the two groups were detected before and after treatment.The recovery time of serum amylase,resumed oral intake time, hospitalization time and hospitalization expenses of the two groups were observed.The occurrence of gastrointestinal complications was observed in the two groups during the treatment period.Results Compared with before treatment, after treatment Hb,ALB,PA,TFN of the two groups were significantly increased （t =4.114,7.540,5.556,8.307 and 1.994,3.970,2.906,5.099,all P 〈0.05）.After treatment,ALB,PA,TFN of the observation group were higher than the control group （t =2.249,2.256,3.630,all P 〈0.05）.After treatment,recovery time of serum amylase,resumed oral intake time,hospitalization time and hospitalization expenses of the observation group were lower than the control group （t =3.191,5.245,4.846,8.762,all P 〈0.05）.The incidence rate of gastrointestinal complications of the observation group was 11.8%（6 /51）,and that of the control group was 15.2%（7 /46）,the difference was not statis-tically significant （χ2 =0.248,P 〉0.05）.Conclusion In the treatment of severe acute pancreatitis,individualized nutritional support has better curative effect,low incidence of complications,with good clinical application value.
出处
《中国基层医药》
CAS
2016年第22期3423-3426,共4页
Chinese Journal of Primary Medicine and Pharmacy
关键词
营养疗法
胰腺炎
肠外营养支持
肠内营养支持
Nutrition therapy
Pancreatitis
Parenteral nutrition support
Enteral nutrition support
