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联合用药对慢性肺源性心脏病心力衰竭的疗效对比探讨 被引量:12

Comparative Study of the Effect of Combined Therapy on Chronic Pulmonary Heart Disease with Heart Failure
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摘要 目的分析酚妥拉明与多巴胺联合治疗慢性肺源性心脏病心力衰竭的效果.方法:选取我院于2015年3月~2016年2月收治的100例慢性肺源性心脏病心力衰竭患者,分两组,每组各50例患者.对照组接受常规消炎抗感染、强心、平喘、利尿、祛痰等-般支持性治疗.观察组除了接受对照组的所有治疗外,还联合酚妥拉明和多巴胺药物治疗.比较两组患者的治疗效果.结果:治疗后,患者的心脏指数,动脉血氧分压和血氧饱和度各项指标都有所好转,治疗后与治疗前比较,差异有显著性(P〈0.05),另外治疗后,观察组患者的心脏指数,动脉血氧分压和血氧饱和度各项指标都与对照组比较,有显著性(P〈0.05).临床症状均有所改善,观察组中总好转率为98.0%,对照组中总好转率为66.0%,观察组临床疗效显著优于对照组有显著性(P〈0.05).结论:将酚妥拉明与多巴胺两者进行联合用药治疗,可明显改善慢性肺源性心脏病心力衰竭患者的心功能和临床症状,能提高疗效果. Objective: To observe phentolamine and dopamine combination clinical results for the treatment of chronicpulmonary heart disease, heart failure. Methods:100 patients with chronic pulmonary heart disease patients with heartfailure in Our hospital from March 2015 to February 2016,Randomly divided into control group and observation group,50patients in each group.The control group received conventional anti-inflammatory anti-infective,cardiac, asthma,diuretic.Expectorant general supportive therapy.In addition to receiving all the treatment groups was observed in the control group,but also the United phentolamine and dopamine medication. Were compared patient outcomes.Results: After treatment,thepatient's cardiac index, arterial oxygen pressure and oxygen saturation are the indicators have improved compared withbefore treatment after treatment, the difference was significant (P〈0.05), additional treatment, observation group of patientswith cardiac index, arterial oxygen pressure and oxygen saturation of the indicators are compared with the control group,there was a significant (P〈0.05).Clinical symptoms were improved,the overall improvement in the observation groupwas 98.0% in the control group,the total improvement rate was 66.0%, the clinical efficacy of the observation group wassignificantly better than the control group was significant (P〈0.05). Conclusion: The phentolamine and dopamine were bothcombination therapy, treatment failure in patients with chronic pulmonary heart disease, can significantly improve cardiacfunction and clinical symptoms, can improve the efficacy of fruit, worth promoting.
作者 杨琼 张发尧
出处 《中国医药导刊》 2016年第10期1039-1041,共3页 Chinese Journal of Medicinal Guide
关键词 慢性肺源性心脏病 心力衰竭 酚妥拉明 多巴胺 Chronic pulmonary heart disease Heart failure Phentolamine Dopamine
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