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MicroRNA-143与常见肿瘤关系的研究进展 被引量:2

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摘要 MicroRNAs(miRNAs)是一类内源性的长度约18~25个核苷酸的非编码单链RNA分子,目前的研究证实,约半数miRNAs的上游基因位于染色体内与肿瘤相关的区域中,在肿瘤的发生与发展过程中既可扮演癌基因也可扮演抑癌基因的角色,其中MicroRNA143(miR-143)在多种肿瘤中呈低表达,通过多种作用机制发挥类似于抑癌基因的作用,本文就miR-143与肿瘤的研究进展作一综述。
作者 谭亚 周贤
出处 《西南军医》 2016年第6期555-558,共4页 Journal of Military Surgeon in Southwest China
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