摘要
目的 了解西安市不同大气污染程度地区不良妊娠结局的发生现况。方法 选取西安市主城区和城乡结合区作为研究地点，采用分层多阶段随机抽样方法，以问卷调查方式收集2010-2013年怀孕且怀孕结局明确的育龄妇女妊娠相关信息。结果 西安市主城区SO2年平均浓度（38-54 μg/m3）高于城乡结合区（29-43 μg/m3），NO2年平均浓度（29-87 μg/m3）高于城乡结合区（22-42 μg/m3）；主城区的出生缺陷发生率（2.1%）高于城乡结合区（1.0%），差异有统计学意义（P〈0.05）。运用logistic回归模型控制混杂因素后，主城区出生缺陷发生的危险性仍高于城乡结合区，差异有统计学意义（P〈0.05）。其他不良妊娠结局的发生在主城区和城乡结合区之间的差异无统计学意义。结论 大气污染与不良妊娠结局有关。
Objective To compare the differences in the incidence of adverse pregnancy outcome in different area, and confirm if the incidence of adverse pregnancy outcomes is closely associated with air pollution. Methods A cross-sectional study was conducted in the central urban area and the rural-urban area of Xi＇an through a questionnaire survey conducted among the local reproductive women selected through multistage stratified random sampling during 2010-2013, all the reproductive women surveyed were in pregnancy or had definite pregnancy outcomes. Results The annual average of SO2 concentration in the central urban area was 38-54 μg/m3, higher than that in the rural-urban area （29-43 μg/m3）. The annual average NO2 concentration in the central urban area was 29-87 μg/m3, higher than that in the rural-urban area （22-42 μg/m3）. The incidence of birth defects was higher in the central urban area than in the rural-urban area （2.1% vs. 1.0%）, the difference was significant （P〈0.05）. After adjusting for confounding factors, logistic regression analysis showed the incidence of birth defects in the central urban area was still significantly higher than that in the rural-urban area, the difference was significant （P〈0.05）. Conclusion The incidence of adverse pregnancy was closely associated with the level of air pollution.
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
2016年第11期1473-1475,共3页
Chinese Journal of Epidemiology
基金
国家自然科学基金（81230016）
关键词
大气污染
育龄妇女
妊娠结局
Air pollution
Reproductive women
Pregnancy outcome
