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脓毒症炎症反应与内皮细胞损伤研究进展 被引量:7

Research progress of inflammatory reaction and endothelial cells impaired in sepsis
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摘要 脓毒症被定义为机体对感染的异常反应最终引起危及生命的器官功障碍综合征.血管内皮细胞在多种炎症细胞和因子的作用下经历活化一损伤过程是脓毒症发展恶化的中心环节.了解炎症反应与血管内皮损伤关系对理解脓毒症发生发展及其治疗具有重要意义. Sepsis should be defined as life-threatening organ dysfunction caused by a dysregulated host response to infection.Endothelial cells activated and impaired by inflammatory cells or cytokines have an important role in the development of sepsis.Thus,understanding the relationship between inflammatory response and vascular endothelial injury has an important significance for the development and treatment of sepsis.
出处 《国际免疫学杂志》 CAS 2016年第5期479-483,共5页 International Journal of Immunology
基金 广东省科技计划项目(2012A061400010) 广东省广州市科研条件建设项目(7411675081103) 广东省广州市科技计划项目健康医疗协调创新重大专项(201508020253) 广东省广州市科技计划项目科学研究专项(2014J4100033)
关键词 脓毒症 内皮细胞 免疫细胞 炎症因子 Sepsis Endothelial cells Immune cells Inflammatory cytokines
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