摘要
目的探讨体外受精-胚胎移植（IVF-ET）胚胎冷冻保存时间对冻融胚胎移植临床妊娠率的影响。方法将361个冻融移植周期按胚胎冷冻保存时间分为三组：1组：冷冻保存时间≤90天;2组：91~360天;3组：≥361天,比较三组间临床妊娠率的差异。结果 2组与1组比较,临床妊娠率显著升高（P〈0.05）,2组与3组比较无显著性差异（P≥0.05）。结论在胚胎冷冻保存90天内行解冻胚胎移植临床妊娠率降低;胚胎冷冻保存时间≥361天不影响临床妊娠率。
Objectives：To investigate the influence of embryo cryopreservation time of frozen-thawed embryo transfer on clinical pregnancy rate in in vitro fertilization Embryo transfer. Methods：361 frozen-thawed embryo transfer cycles were analyzed retrospectively. Cases were divided into 3 groups according to embryo cryopreservation time（Group 1：≤90 days;Group 2：91~360 days;Group 3：≥361 days）,and clinical pregnancy rate were compared between groups. Results：There was a significant increase in clinical pregnancy rate in Group 2 when compared with those in Group 1（P〈0.05）. Clinical pregnancy rate showed no significant difference between Group 2 and Group 3（P≥0.05）. Conclusions：1. Clinical pregnancy rate was low when frozen-thawed embryo transfer was performed at≤90 days of embryo cryopreservation. 2. There was no decrease in clinical pregnancy rate when frozen-thawed embryo transfer was performed at ≥361 days of embryo cryopreservation.
出处
《中国优生与遗传杂志》
2016年第9期113-114,共2页
Chinese Journal of Birth Health & Heredity
基金
北京市扬帆项目资助(ZYLX201510)
北京市医管局登峰计划项目资助(DFL20151301)
关键词
体外受精-胚胎移植
冷冻胚胎移植
冷冻保存时间
临床妊娠率
In vitro fertilization ＆ Embryo transfer
Frozen-thawed embryo transfer
Cryopreservation storage time
Pregnancy rate
