摘要
目的：分析2012—2013年中国城市癌症早诊早治项目中乳腺癌筛查情况。方法于2012—2013年，对中国9个省份（东部：北京、河北、辽宁、山东和广东；中部：黑龙江和湖南；西部：重庆和甘肃）14个城市中40~69岁（以身份证上的出生日期为准）的当地户籍常住女性（在当地居住3年以上）进行高危风险评估，对17104名乳腺癌高危人群进行乳腺癌筛查，对其中年龄数据完整的12440名调查对象进行了最终分析。40~44岁女性采用超声检查，乳腺影像报告和数据系统（BI-RADS）3级以上结果用X线摄影检查；45岁以上女性采用超声检查结合X线摄影检查。判断标准：BI-RADS 3级为可疑阳性，BI-RADS 4级以上为阳性。采用χ2检验比较不同特征调查对象乳腺癌筛查结果。结果截至2013年10月，12440名调查对象中，东部、中部和西部地区分别占55.43%（6895名）、21.45%（2669名）和23.12%（2876名）；40~44岁占5.5%（684名），≥45岁占94.50%（11756名）。BI-RADS 3级病例2018例，检出率为16.22%；BI-RADS 4级以上病例289例，检出率为2.32%。东部、中部和西部地区BI-RADS 3级检出率分别为19.00%（1310例）、13.75%（367例）和11.86%（341例）（χ2=91.45，P〈0.001），3个地区BI-RADS 4级以上检出率分别为2.41%（166例）、1.54%（41例）和2.85%（82例）（χ2=11.04，P=0.004）。50~54岁人群的BI-RADS 3级检出率较高，为18.74%（561/2994），40~44岁人群BI-RADS 4级以上检出率较高，为2.92%（20/684）。结论西部地区和40~44岁人群的BI-RADS 4级以上检出率较高，中部地区和60~64岁人群较低；东部地区和50~54岁人群BI-RADS 3级检出率较高，西部地区和60~64岁人群较低。
Objective To analyze results of breast cancer screenings in the Cancer Screening Program in Urban China （CanSPUC） during 2012-2013. Methods In 14 cities of 9 provinces （Eastern Region： Beijing, Hebei, Liaoning, Shandong and Guangdong; Central Region： Heilongjiang and Hunan;Western Region： Chongqing and Gansu）, 198 097 women aged 40-69 years who had lived in their cities for ≥3 years were surveyed through a cancer risk assessment questionnaire during 2012-2013. The questionnaires identified women considered to be at high risk for breast cancer, of whom 17 104 received screening examinations, for whom complete records of breast cancer screening and other data were available for 12 440 subjects altogether, including breast ultrasound exams for subjects 40-44 years old. Subjects older than 45 years or in whom breast imaging reporting and data system （BI-RADS） ultrasound had found≥3 lesions also underwent mammography. In this cohort, BI-RADS 3 class was defined as suspicious and＆amp;nbsp;BI-RADS ≥4 class as positive. Chi-square tests were used to compare breast cancer screening results by groups. Results As of October 2013, breast cancer screening percentages for the 12 440 subjects for whom full data were available were, by region, Eastern： 55.43% （6 895）; Central： 21.45% （2 669）; and Western：23.12% （2 876）; by age, 40-44 years： 5.50% （684）; ≥45 years： 94.50% （11 756）. Using BI-RADS, 2018 subjects were found to have 3 lesions （detection rate：16.22%）, which were distributed regionally as Eastern：19.00% （1 310 women）, Central： 13.75% （367） and Western; 11.86% （341）; χ2=91.45, P〈0.001; and 289 were found to have≥4 lesions （detection rate：2.32%）, which were distributed regionally as Eastern：2.41%（166）, Central：1.54%（41） and Western;2.85%（82）;χ2=11.04, P=0.004. Women aged 50-54 years had the highest detection rate of BI-RADS 3 lesions at 18.74% （561/2 994）, and those aged 40-44 years had the highest detection rate of BI-RADS ≥4 at 2.92% （20/684）. Conclusion Detection rates of BI-RADS ≥4 lesions were highest in the Western region and in women aged 40-44 years, and lowest in the Central region and in women aged 60-64 years. Detection rates of BI-RADS 3 lesions were highest in the Eastern region and in women aged 50-54 years and the lowest in the Western region and in women aged 60-64 years.
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2016年第10期887-892,共6页
Chinese Journal of Preventive Medicine
基金
国家重大公共卫生服务项目
关键词
乳腺肿瘤
筛查
乳腺超声
乳腺X线摄影
高危人群
Breast tumor
Screening
Breast ultrasound
Breast mammography
High-risk population
