摘要
目的探讨腹腔镜下前列腺癌根治术与开放手术治疗早期前列腺癌对尿流动力学和生活质量的影响。方法选取2011年10月至2015年10月期间收治的120例前列腺癌患者,分别采用腹腔镜下前列腺癌根治术(观察组)与开放手术(对照组)治疗,每组各60例。比较两组术中情况、术后肠道功能恢复情况,不良反应发生情况、尿流动力学参数和生活质量情况。结果观察组术中出血量、手术时间、住院时间、引流管拔出时间和住院费用均低于或短于对照组(P<0.05);观察组充盈期膀胱顺应性值(BC)、逼尿肌不稳定(DI)发生率、残余尿量(PVR)均低于对照组,而最大尿流率(Qmax)、最大尿流率时逼尿肌压力(Pdet at Qmax)高于对照组(P<0.05);观察组不良反应发生率低于对照组(P<0.05);术前两组生活质量评分无显著差异(P>0.05);术后1个月、3个月和6个月观察组评分高于对照组,差异有统计学意义(P<0.05)。结论与开放手术相比,腹腔镜下前列腺癌根治术操作较简单,对机体创伤小,住院时间短,住院费用较低,尿流动力学恢复程度好,术后并发症发生率低,患者术后生活质量高,值得临床推广应用。
Objective To investigate the influence of laparoscopic radical pmstatectomy and open surgery on urodynamics and life quality for early prostate cancer. Methods 120 cases of prostate cancer patients were treated from October 2011 to October 2015, respectively by lapare- scopic radical pmstatectomy（ observation group） and open surgery（control group） treatment, 60 cases in each group. The intraoperative status, postoperative recovery of bowel function, and urodynamic parameters, adverse reactions, urodynamics and life quality were compared. Results The blood loss, operative time, hospital stay, time to pull out the drainage tube and hospital costs in the observation group were lower or shorter than those of the control group （ P 〈 0.05 ）. BC, DI, PVR, the Qmax and Pdetat Qmax were lower than those of the control group （ P 〈 0.05 ）. The incidence of adverse reactions in the observation group was than lower than the control group （ P 〈0.05 ）. The score of the quality of life in the two groups no significant difference preoperative （ P 〉 0.05 ）. After a month, 3 months and 6 months scores in the observation group were higher than that of the control group, the difference was statistically significant （ P 〈 0.05）. Conclusion Compared with open surgery, laparo- scopic radical prostatectomy operation is relatively simple, with less the body trauma, shorter hospital stay, lower hospital costs, better urodynamic recovery, lower complication rate, higher quality of life after surgery. It is worthy of promotion.
出处
《临床和实验医学杂志》
2016年第21期2102-2104,共3页
Journal of Clinical and Experimental Medicine
基金
2015年上海市卫生和计划生育委员会科研课题(青年项目
编号20154Y0048)
关键词
前列腺癌
腹腔镜
尿流动力学
生活质量
Prostate cancer
Laparoscopic
Urodynamics
Quality of life
