摘要
目的探讨单侧或双侧经椎弓根入路行椎体后凸成形术(PKP)对骨质疏松性椎体压缩骨折患者短期与中期预后的影响,为临床治疗提供参考依据。方法选择2012年1月至2014年1月收治的64例骨质疏松性椎体压缩性骨折患者作为研究对象,根据不同术式分为单侧经椎弓根入路行PKP组(单侧组)和双侧经椎弓根入路行PKP组(双侧组),每组32例。比较两组患者的手术情况及Cobb角、椎体前缘高度丢失率、椎体中间高度丢失率和疼痛程度(VAS)评分。结果双侧组手术时间、骨水泥注入量明显高于单侧组(P<0.05);术后1周、12个月,两组患者Cobb角、椎体前缘高度丢失率、椎体中间高度丢失率比较差异均无统计学差异(P>0.05);术后24个月,双侧组Cobb角、椎体前缘高度丢失率、椎体中间高度丢失率均明显低于单侧组(P<0.05);术后1周及12、24个月,两组患者VAS评分比较差异均无统计学差异(P>0.05);两组骨水泥渗漏发生率比较差异无统计学意义(P>0.05)。结论单侧或双侧入路经椎弓根行PKP均是治疗骨质疏松性椎体压缩骨折的有效术式,短期预后相近,但随着时间延长,双侧入路更有利于维持患者椎体高度和矫正后凸畸形,值得临床重视。
Objective To investigate the short and medium term prognosis of PKP in osteoporotic vertebral compression fractures with uni- lateral or bilateral pedicle, to provide reference for clinical treatment. Methods From January 2012 to January 2014, 64 patients with osteoporot- ic vertebral compression fractures were selected as study subjects, accm＇ding to different operation type, the patients were divided into unilateral PKP group （unilateral group） and bilateral pedicle approach group PKP （bilateral group）, each group of 32 cases. The operation condition and Cobb angle, anterior height loss rate of vertebral body, middle height loss rate and pain degree （VAS） score were compared between the two groups. Results The operation time, bone cement injection volume in bilateral group were significantly higher than those of the unilateral group （ P 〈0.05）. 1 week and 12 months after operation, there was no significant difference in the rate of loss of Cobb angle between the two groups of patients, and the loss rate of the middle height of the vertebral body （ P 〉 0.05 ）. 24 months after operation, the Cobb angle, anterior height loss rate of vertebral body, high loss rate of bilateral group were significantly lower than that of unilateral group （ P 〈 0.05 ）. 1 weeks and 12,24 months after operation, there was no significant difference in VAS scores between the two groups （ P 〉 0.05）. There was no significant difference in the incidence of cement leakage between the two groups （ P 〉 0.05 ）. Conclusion Unilateral or bilateral into the path of transpedicular PKP is an effective operation for the treatment of osteoperotic vertebral compression fractures, short - term prognosis is similar, but with the extension of time, bilateral approach is more conducive to maintain with the vertebral height and correct kyphosis. It is worthy of clinical attention.
出处
《临床和实验医学杂志》
2016年第21期2143-2146,共4页
Journal of Clinical and Experimental Medicine
关键词
骨质疏松性椎体压缩骨折
椎体后凸成形术
单侧
双侧
预后
Osteoperotic vertebral compression fractures
Percutaneous kyphoplasty
Unilateral
Bilateral
Prognosis
