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右美托咪定与咪达唑仑用于麻醉性监护效果比较

Comparison of Dexmedetomidine and Midazolam for Anesthesia Care Effect
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摘要 目的比较右美托咪定与咪达唑仑局麻下乳房肿块切除手术中麻醉性监护效果。方法选择50例局麻下择期乳房肿块切除术的患者按随机数字表法分为咪达唑仑组(M组)和右美托咪啶组(D组)。分析各时间点两组MAP、HR、SpO_2、OAA/S评分。结果 T_1、T_2,T_3时间点两组MAP明显低于T0(P<0.05)。D组用药后T_1、T_2,T_3的HR明显慢于T0(P<0.05),且慢于M组相同时间点(P<0.05)。两组OAA/S评分均较前降低(P<0.05),D组用药后T_1、T_2时间点OAA/S评分均高于M组(P<0.05)。结论相比咪达唑仑,右美托咪定心率降低更为显著,但镇静效果更好。 Objective To compare the effects of dexmedetomidine and midazolam under local anesthesia for breast tumor surgery effect of monitored anesthesia care. Methods 50 cases under local anesthesia for elective resection of breast lumps patients were randomly divided into midazolam group(group M) and dexmedetomidine group(group D). Analysis of the time point of two groups of MAP, HR, Sp O2, OAA/S score. Results T1, T2, T3 time point two groups of MAP was significantly lower than T0(P0.05). D group after treatment, T2, T3, HR of T1 was significantly slower than T0(P0.05), Wait a minute in the M group at the same time(P0.05). The OAA/S scores of the two groups were lower than before(P0.05). The OAA/S and T2 time points were higher in group T1 than in group M(P0.05) after treatment in group D. Conclusion Compared with midazolam, dexmedetomidine heart rate decreased significantly, but the sedative effect is better.
出处 《中国继续医学教育》 2016年第31期66-67,共2页 China Continuing Medical Education
关键词 右美托咪定 咪达唑仑 麻醉 Dexmedetomidine Midazolam Anaesthesia
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