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稳心颗粒对慢性肺源性心脏病患者右心功能的影响

Effect of Buchangwenxin Granules on Right Heart Function in Patients with Chronic Pulmonary Heart Disease
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摘要 目的:探讨稳心颗粒对慢性肺源性心脏病(CPHD)患者右心功能的影响。方法:86例CPHD患者随机分为观察组和对照组,各43例。两组均给予抗感染、平喘、利尿基础治疗,观察组加用稳心颗粒9g/次,3次/d,疗程4周。超声心动图监测两组治疗前后右心室的舒张早期最大血流速度(E峰)、舒张晚期最大血流速度(A峰)、三尖瓣环运动幅度(TAPSE)及右室面积变化分数(RVFAC)。结果:治疗后两组E峰、A峰、E/A比值及TAPSE、RVFAC较治疗前均改善。观察组E峰、A峰、E/A比值较对照组改善显著,TAPSE、RVFAC与对照组相比无显著差异。结论:稳心颗粒能显著改善CPHD患者的右心舒张功能。 Objective: To investigate the effect of Buchangwenxin Granules on right ventricular function in patients with chronic pulmonary heart disease(CPHD). Methods: 86 cases of CPHD were randomly divided into observation group and control group, each of 43 cases. The two groups were given anti infection, antiasthmatic, diuretic therapy, observation group were treated with Buchangwenxin Granules 9g/times, 3 times/d, 4 weeks. Echocardiography monitoring early diastolic peak velocity of right ventricle(E peak), late diastolic peak flow velocity(A peak), three tricuspid annular motion amplitude(TAPSE) and right ventricular fractional area change(RVFAC) of the two groups before and after the treatment. Results: After the treatment, the two groups of E peak, A peak, E/A ratio and TAPSE, RVFAC than before treatment were improved. The observation group E peak, A peak, E/A ratio improved significantly compared with the control group, RVFAC, TAPSE compared with the control group, there was no significant difference. Conclusion: Buchangwenxin Granules can significantly improve the right ventricular diastolic function in patients with CPHD.
作者 王立立 耿彦平 许玉芳 杜荣品 苑可心 郝清卿 Wang Li-li Geng Yan-ping Xu Yu-fang et al(Department of Cardiology, Hebei General Hospital, Shijiazhuang 050051, China)
出处 《中国医药导刊》 2016年第11期1134-1135,共2页 Chinese Journal of Medicinal Guide
关键词 稳心颗粒 慢性肺源性心脏病 心室功能 Buchangwenxin Granules Chronic pulmonary heart disease Ventricular function
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