摘要
目的观察间断血液透析在治疗顽固性心衰并急性肾损伤的疗效。方法选取2014年1月—2016年1月华北理工大学附属医院心内科住院的利尿剂抵抗药物治疗无效的顽固性心衰并急性肾损伤患者23例,均给予间断血液透析治疗,观察临床疗效。结果治疗后患者的心衰症状均得到明显缓解,肺水肿或肺淤血消失;尿素氮、血肌酐、血压、心率、血氧饱和度、左心室射血分数、氨基末端B型脑钠肽前体(BNP)有明显改善,治疗前后比较差异有统计学意义(P<0.05);并恢复对利尿剂的敏感性,停止透析及超滤,继续使用药物维持治疗。结论间断血液透析治疗顽固性心衰并急性肾损伤效果显著,并可恢复患者对利尿剂的敏感性。
Objective To observe the effects of intermittent hemodialysis（IHD） in patients with refractory heart failure and diuretic resistance. Methods Twenty-three patients with refractory heart failure and diuretic resistance were selected as the subject in author＇s hospital from January 2014 to January 2016, and giving all of them the treatment of drugand intermittent hemodialysis （simple ultrafiltration or ultrafiltration ＋ hemodialysis）. Results After treatment, patients＇symptom on heart failure was obviously relief, pulmonary edema and Pulmonary congestion were also disappeared, whose BUN, SCr, BP, HR, SpO2, LVEF and BNP were all improved. There was statistical significance before and after treatment （P〈0. 05）. Conclusion Intermittent hemodialysis has the significant effect in paitients with refractory heart failure and diuretic resistance.
出处
《中国煤炭工业医学杂志》
2016年第11期1584-1586,共3页
Chinese Journal of Coal Industry Medicine
关键词
血液透析
顽固性心力衰竭
药物治疗
Hemodialysis
Refractory heart failure
Diuretic resistance
drug therapy
