摘要
目的探讨慢性阻塞性肺疾病(COPD)患者抑郁情况及其影响因素。方法选取2013年3月—2016年1月在中国人民解放军第180医院呼吸内科住院部和门诊部就诊的COPD患者206例,通过电子病历系统记录其一般资料〔包括性别、年龄、吸烟史、受教育程度、体质指数(BMI)和COPD分级〕,采用肺功能仪检查患者肺功能〔包括第1秒用力呼气容积与用力肺活量比值(FEV1/FVC)和第1秒用力呼气容积占预计值百分比(FEV_1%pred)〕,采用医院焦虑抑郁量表(HAD)评估患者抑郁情况,采用多因素logistic回归分析筛选COPD患者抑郁的影响因素。结果本组患者抑郁发生率为41.3%(85/206)。抑郁患者和非抑郁患者FEV1/FVC比较,差异无统计学意义(P>0.05);抑郁患者和非抑郁患者性别、年龄、有无吸烟史、受教育程度、BMI、COPD分级及FEV1%pred比较,差异均有统计学意义(P<0.05)。多因素logistic回归分析结果显示,性别〔OR=0.457,95%CI(0.210,0.993)〕、年龄〔OR=0.617,95%CI(0.428,0.890)〕、受教育程度〔OR=1.455,95%CI(1.099,1.927)〕、BMI〔OR=0.492,95%CI(0.291,0.833)〕、COPD分级〔OR=1.946,95%CI(1.003,3.779)〕及FEV1%pred〔OR=2.337,95%CI(1.523,3.587)〕为COPD患者抑郁的影响因素(P<0.05)。结论 COPD患者抑郁发生率较高,而性别、年龄、受教育程度、BMI、COPD分级及FEV1%pred为COPD患者抑郁的影响因素。
Objective To investigate the occurrence dynamics of depression in patients with chronic obstructive pulmonary disease（ COPD） and the influencing factors. Methods From March 2013 to January 2016 in the In - patient Department and Out - patient Department of Department of Respiratory Medicine,the 180th Hospital of Chinese People＇ s Liberation Army,a total of 206 patients with COPD were enrolled. Electronic medical record was used to collect the general information（including gender,age,smoking history,educational status,BMI and COPD grade）,pulmonary function detector was used to detect the index of pulmonary function（including FEV1 / FVC and FEV1% pred）,Hospital Anxiety and Depression Scale（HAD）was used to evaluate the incidence of depression,and multivariate logistic regression analysis was used to analyze the influencing factors of depression in patients with COPD. Results The incidence of depression was 41. 3% （85 / 206）. No statistically significant differences of FEV1 / FVC was found in patients with or without depression（P ﹥ 0. 05）,while there were statistically significant differences of gender,age,with smoking history or not,educational status,BMI,COPD grade and FEV1% pred in patients with or without depression（P ﹤ 0. 05）. Multivariate logistic regression analysis showed that,gender〔OR = 0. 457,95% CI（0. 210,0. 993）〕,age〔 OR = 0. 617,95% CI（0. 428,0. 890）〕,educational status〔 OR =1. 455,95% CI（1. 099,1. 927）〕,BMI〔OR = 0. 492,95% CI（0. 291,0. 833）〕,COPD grade〔 OR = 1. 946,95% CI （1. 003,3. 779）〕 and FEV1% pred〔 OR = 2. 337,95% CI（1. 523,3. 587）〕were influencing factors of depression in patients with COPD（P ﹤ 0. 05）. Conclusion The incidence of depression is relatively high in patients with COPD;gender, age,educational status,BMI,COPD grade and FEV1% pred were influencing factors of depression in patients with COPD.
作者
洪丽月
洪原城
黄种杰
金润女
HONG Li-yue HONG Yuan-cheng HUANG Zhong-jie JIN Run-nyu(Department of Respiratory Medicine, the 180th Hospital of Chinese People＇s Liberation Army, Quanzhou 352000, China)
出处
《实用心脑肺血管病杂志》
2016年第6期42-45,共4页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
基金
2014军区医学科技创新资助项目(14MS093)
关键词
肺疾病
慢性阻塞性
抑郁
影响因素分析
Pulmonary Disease,chronic obstructive
Depression
Root cause analysis
