摘要
目的:观察血府逐瘀汤对高血压合并左室肥厚(LVH)患者血清超敏C反应蛋白(hs-CRP)及血管紧张素血管紧张素Ⅱ的(AngⅡ)影响及临床疗效。方法:将116例高血压合并LVH者随机观察组和对照组,每组各58例,对照组给予西医常规治疗,观察组在对照组的基础上给予血府逐瘀汤治疗,两组均连续治疗3个月。结果:两组治疗后收缩压(SBP)及舒张压(SDP)及心率(HR)等有一定程度的下降(P<0.05),观察组患者上述指标的改善情况优于对照组(P>0.05),观察组治疗后临床症状如心悸、胸闷、胸痛、气促的改善情况优于对照组(P<0.05);治疗后两组患者的LVPWT、LVDd、IVST及LVMI均较治疗前有所下降(P>0.05),观察组的上述指标改善情况由于对照组(P>0.05)。结论:自拟血府逐瘀汤能够显著缓解高血压合并LVH患者临床症状、抑制左室肥厚,其作用机制可能与降低此类患者的炎性反应及AngⅡ水平有关。
Objective：To observe the therapeutic of hypertension with left ventricular hypertrophy（LVH）in patients with serum hypersensitive c-reactive protein（hs-CRP）and angiotensin angiotensinⅡ（AngⅡ）effects and clinical efficacy.Methods：116cases of hypertension with LVH random observation group and control group,each group of58 cases,control group given conventional western medicine treatment,the observation group in the control group to give Xuefu Zhuyu decoction,on the basis of the two groups are continuous treatment for 3months.Results：Two groups after treatment systolic blood pressure（SBP）and diastolic blood pressure（SDP）and heart rate（HR）had a certain degree of decline（P〈0.05）,the observation group of patients above indicators of improvement was better than that of control group（P〈0.05）,observation group after treatment of clinical symptoms such as palpitations,chest tightness,chest pain,shortness of breath,the improvement of the situation was better than that of control group（P〈0.05）;in the two groups after treatment in patients with LVPWT,LVDd,IVST and LVMI was dropped（P〈0.05）,the index of the observation group to improve the situation due to the control group（P〈0.05）.Conclusions：The therapeutic can significantly relieve hypertension with LVH in patients with clinical symptoms,inhibiting left ventricular hypertrophy and its mechanism may be related to reduce inflammatory reaction in patients with and Ang Ⅱlevel.
作者
孙晓红
陈学彬
Sun Xiaohong Chen Xuebin(FirstClinical Medical of Shaanxi University of Traditional Chinese Medicine （Xianyang 712046)
出处
《陕西中医》
2016年第11期1455-1457,共3页
Shaanxi Journal of Traditional Chinese Medicine
关键词
高血压/中西医结合疗法
血府逐瘀汤/治疗应用
Hypertension/integrated Chinese traditional and western medicine therapy
Xue Fu Zhu Yu Tang/therapeutic uses
