摘要
非动脉炎性前部缺血性视神经病变（non-arteritic anterior ischemic optic neuropathy,NAION）是临床上常见的一种急性视神经病变,严重危害视功能.NAION的眼局部危险因素包括小视盘或小视杯、视盘玻璃膜疣、眼压变化、全身疾病相关性眼病等;全身性危险因素包括高血压、糖尿病、高脂血症、动脉粥样硬化、阻塞性睡眠呼吸暂停综合征、凝血功能异常、夜间低血压、应用某些药物如磷酸二酯酶-5抑制剂、α-干扰素、胺碘酮等.但目前尚未明确其详细的发病机制及有明确关系的致病因素.本文就目前NAION的发病机制及危险因素做一简要综述.
Non-arteritic anterior ischemic optic neuropathy（NAION） is a common clinical kind of acute optic neuropathy and very harmful to visual function.Ocular risk factors for NAION include small disc or small cup,optic disc drusen,intraocular pressure change,systemic disease associated ophthalmopathy.Systemic risk factors include hypertension,diabetes,hyperlipidemia,atherosclerosis,obstructive sleep apnea syndrome （OSAS）,abnormal blood coagulation,nocturnal hypotension,and using some drugs such as phosphodiesterase 5 inhibitors,interferon alpha,and amiodarone.However,it has not yet been clear about the pathogenesis and related pathogenic factors about NAION.This article gives a brief summary about the pathogenesis and risk factors of NAION.
出处
《国际眼科纵览》
2016年第5期310-315,共6页
International Review of Ophthalmology
