摘要
目的探讨2型糖尿病患者不同发展阶段的生活质量及其影响因素,为提高2型糖尿病患者生活质量提供参考依据。方法随机抽取2011年6月—2014年10月在广东医学院附属医院内分泌科就诊的697例2型糖尿病患者进行问卷调查、体格检查和实验室检测。结果有并发症2型糖尿病患者躯体角色、躯体疼痛、总体健康、精力、情绪角色、心理健康和综合评分得分分别为(42.3±29.7)、(69.1±24.4)、(44.6±23.5)、(60.8±22.1)、(58.8±32.8)、(63.2±21.5)和(63.1±19.6)分,均低于无并发症2型糖尿病患者的(70.5±36.4)、(77.6±22.5)、(66.1±20.7)、(73.8±24.3)、(68.0±33.2)、(78.9±16.9)和(75.9±21.3)分,差异均有统计学意义(均P<0.001);多元线性逐步回归分析结果显示,文化程度、月人均收入、胰岛素越低,体质指数、餐前血糖、餐后2 h和4 h血糖、餐后2 h和4 h糖化血红蛋白越高,有并发症的2型糖尿病患者生活质量越差;胰岛素越低,体质指数、餐前血糖和糖化血红蛋白、餐后2 h和4 h血糖、餐后2 h和4 h糖化血红蛋白越高,无并发症的2型糖尿病患者生活质量越差。结论 2型糖尿病患者不同发展阶段生活质量不同;体质指数、餐前血糖、餐后2 h和4 h血糖、餐后2 h和4 h糖化血红蛋白、胰岛素是2型糖尿病患者生活质量的主要影响因素。
Objective To explore the status and influencing factors of quality of life （QOL） among type 2 diabetic patients at different stages and to provide references for improving QOL of the patients. Methods A total of 697 type 2 diabetes outpatients visiting endocrinology of Affiliated Hospital of Guangdong Medical College were recruited and sur- veyed with Medical Outcomes Study 36-Item Short Form Health Survey （ SF-36 ）, physical examination and laboratory test from June 2011 to October 2014. Results The type 2 diabetic outpatients with complications had significantly lower SF-36 domain scores for role physical （42. 3 ± 29. 7 vs. 70. 5 ± 36.4）, bodily pain （ 69. 1 × 24. 4 vs. 77.6 ± 22. 5 ）, gen- eral health （44. 6 ±3.5 vs. 66. 1 ±0. 7） ,vitality （60. 8 ±2. 1 vs. 73.8 ±24. 3） ,role emotional （58.8 ±2. 8 vs. 68.0 ±3.2） ,mental health （63.2 ±1.5 vs. 78.9 ±16. 9） ,and overall SF-36 score （63.1 ±19.6 vs. 75.9 ±1.3） compared to those without complications （ all P 〈 0. 001 ）. Multivariate linear stepwise regression analysis showed that the risk factors of lower QOL were low education level,low monthly income per capita,low insulin level, high body mass index （BMI）, high fasting blood glucose （BG）, high 2 and 4 hours postprandial BG, and high 2 and 4 hours postprandial glycosylated hemoglobin among the type 2 diabetes patients with complications;whereas among the patients without com- plications, the risk factors of lower QOL were low insulin level, high BMI ,high fasting BG and glycosylated hemoglobin, high 2 and 4 hours postprandial BG, and high 2 and 4 hours postprandial glycosylated hemoglobin. Conclusion The QOL of type 2 diabetic patients is related to the stage of the diabetes and mainly influenced by their BMI,insulin level, fasting BG ,2 and 4 hours postprandial BG, and 2 and 4 hours postprandial glycosylated hemoglobin.
出处
《中国公共卫生》
CAS
CSCD
北大核心
2016年第11期1506-1509,共4页
Chinese Journal of Public Health
基金
国家自然科学基金(81402771)
广东省医学科研基金(B2013294)
广东教育厅科研平台和项目青年创新人才类项目(2014KQNCX103)
东莞市社会科技发展项目(2013108101056)
湛江市科技攻关项目(2014B01020)
