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miRNA-204与肿瘤关系的研究进展 被引量：6

Research Progress of the Relationship between miRNA-204 and Cancers
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摘要 miRNA-204在人体中广泛表达,并在很多肿瘤中表达异常。miRNA-204在人体内通过对靶基因的调节,在肿瘤的发生发展过程中起重要作用。miRNA-204常作为肿瘤的抑癌基因,且通过相关分子机制可以抑制肿瘤的侵袭、转移,也可以作为潜在的分子标记物用于肿瘤的治疗。对miRNA-204的深入研究,可对肿瘤的预防及治疗提供新思路。 miRNA-204 is widely expressed in human body and also aberrantly expressed in almost all human cancers. It is proved that miRNA-204 plays an important role in the occurrence and development of cancers through regulating its target genes in human body. miRNA-204 is often used as a tumor suppressor to inhibit tumor invasion and metastasis through the related molecular mechanism. Meanwhile,miRNA-204 can also be used as potential molecular marker in the treatment of cancers. With a deeper study of miRNA-204,it is possible to provide new ideas for the prevention and treatment of cancers.
作者 江海波 葛瑞祥 钱冬喜 毛捷
机构地区 皖南医学院弋矶山医院神经外科
出处 《沈阳医学院学报》 2016年第6期479-482,共4页 Journal of Shenyang Medical College
基金 安徽省高校自然科学研究项目(No.KJ2015A141)
关键词 miRNA-204 肿瘤 靶基因 miRNA-204 cancer targetgene research progress
分类号 R730.2 [医药卫生—肿瘤]
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  • 1Douglas Hanahan,Robert A. Weinberg.Hallmarks of Cancer: The Next Generation[J]. Cell . 2011 (5)
  • 2Congcong He,Daniel J. Klionsky.Regulation Mechanisms and Signaling Pathways of Autophagy[J]. Annual Review of Genetics . 2009
  • 3Kevin Sheets,Stephen Wunsch,Colin Ng,Amrinder S. Nain.Shape-dependent cell migration and focal adhesion organization on suspended and aligned nanofiber scaffolds[J].Acta Biomaterialia.2013(7)
  • 4Emily M. Chandler,Bo Ri Seo,Joseph P. Califano,Roberto C. Andresen Eguiluz,Jason S. Lee,Christine J. Yoon,David T. Tims,James X. Wang,Le Cheng,Sunish Mohanan,Mark R. Buckley,Itai Cohen,Alexander Yu Nikitin,Rebecca M. Williams,Delphine Gourdon,Cynthia A. Reinhart-King,Claudia Fischbach.Implanted adipose progenitor cells as physicochemical regulators of breast cancer[J].Proceedings of the National Academy of Sciences.2012(25)
  • 5Olga Mikhaylova,Yiwen Stratton,Daniel Hall,Emily Kellner,Birgit Ehmer,Angela F. Drew,Catherine A. Gallo,David R. Plas,Jacek Biesiada,Jarek Meller,Maria F. Czyzyk-Krzeska.VHL-Regulated MiR-204 Suppresses Tumor Growth through Inhibition of LC3B-Mediated Autophagy in Renal Clear Cell Carcinoma[J].Cancer Cell.2012(4)
  • 6Purva Singh,Cara Carraher,Jean E. Schwarzbauer.Assembly of Fibronectin Extracellular Matrix[J].Annual Review of Cell and Developmental Biology.2010
  • 7David Juan,Gabriela Alexe,Travis Antes,Huiqing Liu,Anant Madabhushi,Charles Delisi,Shridhar Ganesan,Gyan Bhanot,Louis S. Liou.Identification of a MicroRNA Panel for Clear-cell Kidney Cancer[J].Urology.2010(4)
  • 8Janaiah Kota,Raghu R. Chivukula,Kathryn A. O’Donnell,Erik A. Wentzel,Chrystal L. Montgomery,Hun-Way Hwang,Tsung-Cheng Chang,Perumal Vivekanandan,Michael Torbenson,K. Reed Clark,Jerry R. Mendell,Joshua T. Mendell.Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model[J].Cell.2009(6)
  • 9Kandice R. Levental,Hongmei Yu,Laura Kass,Johnathon N. Lakins,Mikala Egeblad,Janine T. Erler,Sheri F.T. Fong,Katalin Csiszar,Amato Giaccia,Wolfgang Weninger,Mitsuo Yamauchi,David L. Gasser,Valerie M. Weaver.Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling[J].Cell.2009(5)
  • 10Mika?l M. Martino,Mayumi Mochizuki,Dominique A. Rothenfluh,Sandra A. Rempel,Jeffrey A. Hubbell,Thomas H. Barker.Controlling integrin specificity and stem cell differentiation in 2D and 3D environments through regulation of fibronectin domain stability[J].Biomaterials.2008(6)

共引文献8

同被引文献35

引证文献6

二级引证文献5

沈阳医学院学报
2016年 第6期

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