摘要
目的研究分析咪唑斯汀与雷尼替丁联用治疗慢性特发性荨麻疹疗效及安全性。方法 2014年5月—2016年5月期间,整群选择该院接收的慢性特发性荨麻疹患者72例作为研究对象,将72例患者随机分为两组,观察组36例和对照组36例,对照组患者应用咪唑斯汀进行治疗,观察组患者应用雷尼替丁联合咪唑斯汀进行治疗,对比观察组与对照组的治疗效果。结果观察组患者治疗前症状积分(2.76±0.65)分与对照组(2.70±0.52)分差异无统计学意义(P>0.05);观察组患者治疗后症状积分(0.73±0.62)分优于对照组(1.59±0.68)分,差异有统计学意义(P<0.05);观察组治疗有效率为97.22%,对照组治疗有效率为80.56%,数据差异有统计学意义(P<0.05);观察组患者不良反应发生率为5.56%,对照组患者不良反应发生率为11.11%,差异无统计学意义(P>0.05)。结论咪唑斯汀与雷尼替丁联用治疗慢性特发性荨麻疹的效果较好,安全性高,值得推广应用。
Objective To study the analysis of ranitidine imidazole westin and adjunctive therapy for chronic idiopathic ur- ticaria efficacy and safety. Methods Group selection May 2014 to May 2016, choose 72 patients with chronic idiopathic ur- ticaria in our hospital to receive as the object of study, 72 patients were randomly divided into two groups, 36 cases obser- vation group and control group 36 cases, control group patients using imidazole sting treatment, joint ranitidine group pa- tients imidazole sting treatment, compared the curative effect of observation group and control group. Results Observation group patients before symptoms （2.76 ± 0.65） points and the control group （2.70±0.52） and no significant difference, there is no statistical significance（P 〉 0.05）; Observation group after treatment in patients with symptoms （0.73 ± 0.62） points is bet- ter than that of control group （1.59±0.68）, significant difference was statistically significant （P 〈 0.05）; Treatment group ef- fective rate was 97.22%, control group treatment effective rate was 80.56%, significantly, the data is statistically signifi- cance （P 〈 0.05）; Observation group of patients the incidence of adverse reactions was 5.56%, control group patients the in- cidence of adverse reactions was 11.11%, the difference is small, no statistical significance （P 〉 0.05）. Conclusion Raniti- dine imidazole westin and adjunctive therapy for chronic idiopathic urticaria effect is good, high safety, is worthy of popu- larization and application.
出处
《中外医疗》
2016年第32期14-16,共3页
China & Foreign Medical Treatment
关键词
咪唑斯汀
雷尼替丁
慢性特发性荨麻疹
疗效
Imidazole sting
Ranitidine
Chronic idiopathic urticaria
The curative effect
