摘要
热休克蛋白(HSP)70在肝细胞癌(HCC)组织中呈不同程度的表达,其表达及调节机制尚不清楚,能否为HCC的早期诊断、治疗及预后提供帮助成为学者们研究的热点。从HSP70来源及家族、在HCC中的异常表达、与HCC各种治疗方法及其预后相关性等方面进行了综述,旨在为HCC的临床诊断及治疗提供帮助。
Heat shock protein 70（ HSP70） is expressed differently in hepatocellular carcinoma（ HCC） tissues. Since its expression and regulatory mechanism remain unclear,whether HSP70 can help with the early diagnosis,treatment,and prognostic evaluation of HCC has become a hot research topic. This article reviews the source of HSP70 and its family,abnormal expression of HSP70 in HCC,and its association with treatment methods and prognostic evaluation of HCC,in order to provide a reference for clinical diagnosis and treatment of HCC.
出处
《临床肝胆病杂志》
CAS
2016年第11期2206-2209,共4页
Journal of Clinical Hepatology
