摘要
目的比较Padua评分、修正的Geneva评分、Caprini评分和Wells深静脉血栓形成(DVT)评分对2型糖尿病(T2DM)患者DVT的预测价值。方法收集2013年1月至2015年12月疑诊DVT的T2DM患者207例,使用Padua评分、修正的Geneva评分、Caprini评分和Wells DVT评分对207例T2DM患者进行DVT预测,比较4种工具的预测效果。结果 Padua评分、修正的Geneva评分、Caprini评分和Wells DVT评分诊断糖尿病合并DVT的受试者工作特征(ROC)曲线下面积分别为0.694±0.038、0.877±0.027、0.656±0.039、0.864±0.028;灵敏度分别为48.75%、80.00%、55.00%、78.75%,特异度分别为81.89%、89.76%、70.08%、88.19%,约登指数分别为0.306 4、0.697 6、0.250 8、0.669 4。修正的Geneva评分和Wells DVT评分的ROC曲线下面积显著高于Padua评分和Caprini评分的ROC曲线下面积,差异均有统计学意义(P<0.01);修正的Geneva评分的ROC曲线下面积与Wells DVT评分的ROC曲线下面积比较差异无统计学意义(P>0.05);Padua评分的ROC曲线下面积与Caprini评分的ROC曲线下面积比较差异无统计学意义(P>0.05)。4种评分灵敏度由高到低分别为修正的Geneva评分>Wells DVT评分>Caprini评分>Padua评分,特异度由高到低分别为修正的Geneva评分>Wells DVT评分>Padua评分>Caprini评分,约登指数由高到低分别为修正的Geneva评分>Wells DVT评分>Padua评分>Caprini评分。结论 Padua评分、修正的Geneva评分、Caprini评分和Wells DVT评分均能在一定程度上预测T2DM患者DVT的发生风险,其中修正的Geneva评分和Wells DVT评分预测价值最高,Padua评分和Caprini评分预测价值略偏低。
Objective To compare the predictive value of the Padua score, revised Geneva score, Caprini score and Wells score for deep vein thrombosis （DVT） in patients with type 2 diabetes meilitus （T2DM）. Methods A total of 207 T2DM patients with suspected DVT were collected from January 2013 to December 2015. The Padua score, revised Geneva score, Caprini score and Wells score were used to predict DVT in 207 patients with T2DM, and the predictive value of the four methods was compared. Results The area under curve （AUC） of the ROC curve of the Padua score, revised Geneva score, Ca- prini score and Wells score for diagnosing DVT in patients with T2DM was 0. 694 ±0. 038,0. 877±0. 027,0. 656 ：t：0. 039 and 0. 864± 0. 028 respectively;the sensitivity was 48.75%, 80.00% , 55.00% and 78.75% respeetively; the specificity was 81.89% ,89.76% ,70.08% and 88.19% respectively;and the Youden index was 0.306 4,0.697 6,0.250 8 and 0.669 4 respec- tively. The AUC of revised Geneva score and Wells score was significantly higher than that of Padua score and Caprini score（ P 〈 0.01 ）. There was no significant difference in the AUC between the revised Geneva score and Wells score（ P 〉 0. 05 ）, and there was no significant difference in the AUC between the Padua score and Caprini score（ P 〉 0.05 ）. The sensitivity of the four kinds of scoring from high to low was the revised Geneva seore, Wells score, Caprini score and Padua score respectively;the specificityof the four kinds of scoring from high to low was revised Geneva score,Wells score,Padua score and Caprini score respectively; and the Youden index of the four kinds of scoring from high to low was the revised Geneva score, Wells score, Padua score and Caprini score respectively. Conclusions The Padua score,revised Geneva score,Caprini score and Wells score could predict the risk of DVT in patients with T2DM in some extent. The predictive value of the revised Geneva score and Wells score for predic- ting DVT is high, but the predictive value of the Padua score and Caprini score is slightly lower.
出处
《新乡医学院学报》
CAS
2016年第11期976-979,共4页
Journal of Xinxiang Medical University
